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Constitutively active Stat5b in CD4+ T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses.
Vogtenhuber C, Bucher C, Highfill SL, Koch LK, Goren E, Panoskaltsis-Mortari A, Taylor PA, Farrar MA, Blazar BR. Vogtenhuber C, et al. Among authors: bucher c. Blood. 2010 Jul 22;116(3):466-74. doi: 10.1182/blood-2009-11-252825. Epub 2010 May 4. Blood. 2010. PMID: 20442366 Free PMC article.
Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia.
Zhou Q, Bucher C, Munger ME, Highfill SL, Tolar J, Munn DH, Levine BL, Riddle M, June CH, Vallera DA, Weigel BJ, Blazar BR. Zhou Q, et al. Among authors: bucher c. Blood. 2009 Oct 29;114(18):3793-802. doi: 10.1182/blood-2009-03-208181. Epub 2009 Sep 1. Blood. 2009. PMID: 19724059 Free PMC article.
Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes.
Hippen KL, Bucher C, Schirm DK, Bearl AM, Brender T, Mink KA, Waggie KS, Peffault de Latour R, Janin A, Curtsinger JM, Dillon SR, Miller JS, Socie G, Blazar BR. Hippen KL, et al. Among authors: bucher c. Blood. 2012 Jan 12;119(2):619-28. doi: 10.1182/blood-2011-07-368027. Epub 2011 Nov 10. Blood. 2012. PMID: 22077059 Free PMC article.
Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis.
May SL, Zhou Q, Lewellen M, Carter CM, Coffey D, Highfill SL, Bucher CM, Matise I, Morse HC 3rd, O'Sullivan MG, Schutten M, Johnson C, Bellgrau D, Blazar BR, Modiano JF. May SL, et al. Among authors: bucher cm. PLoS One. 2014 Jun 19;9(6):e100629. doi: 10.1371/journal.pone.0100629. eCollection 2014. PLoS One. 2014. PMID: 24945807 Free PMC article.
273 results