Reed JC - Search Results

1

BI-97C1, an optically pure Apogossypol derivative as pan-active inhibitor of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.

Wei J, Stebbins JL, Kitada S, Dash R, Placzek W, Rega MF, Wu B, Cellitti J, Zhai D, Yang L, Dahl R, Fisher PB, Reed JC, Pellecchia M. Wei J, et al. Among authors: reed jc. J Med Chem. 2010 May 27;53(10):4166-76. doi: 10.1021/jm1001265. J Med Chem. 2010. PMID: 20443627 Free PMC article.

2

Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins.

Kitada S, Leone M, Sareth S, Zhai D, Reed JC, Pellecchia M. Kitada S, et al. Among authors: reed jc. J Med Chem. 2003 Sep 25;46(20):4259-64. doi: 10.1021/jm030190z. J Med Chem. 2003. PMID: 13678404

3

Cancer prevention by tea polyphenols is linked to their direct inhibition of antiapoptotic Bcl-2-family proteins.

Leone M, Zhai D, Sareth S, Kitada S, Reed JC, Pellecchia M. Leone M, et al. Among authors: reed jc. Cancer Res. 2003 Dec 1;63(23):8118-21. Cancer Res. 2003. PMID: 14678963

4

Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-X(L).

Becattini B, Kitada S, Leone M, Monosov E, Chandler S, Zhai D, Kipps TJ, Reed JC, Pellecchia M. Becattini B, et al. Among authors: reed jc. Chem Biol. 2004 Mar;11(3):389-95. doi: 10.1016/j.chembiol.2004.02.020. Chem Biol. 2004. PMID: 15123268

5

Robust lanthanide-based assays for the detection of anti-apoptotic Bcl-2-family protein antagonists.

Rega MF, Reed JC, Pellecchia M. Rega MF, et al. Among authors: reed jc. Bioorg Chem. 2007 Apr;35(2):113-20. doi: 10.1016/j.bioorg.2006.07.006. Epub 2006 Sep 22. Bioorg Chem. 2007. PMID: 16996562

6

Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1.

Zhai D, Jin C, Huang Z, Satterthwait AC, Reed JC. Zhai D, et al. Among authors: reed jc. J Biol Chem. 2008 Apr 11;283(15):9580-6. doi: 10.1074/jbc.M708426200. Epub 2008 Jan 4. J Biol Chem. 2008. PMID: 18178565 Free PMC article.

7

Bcl-2 antagonist apogossypol (NSC736630) displays single-agent activity in Bcl-2-transgenic mice and has superior efficacy with less toxicity compared with gossypol (NSC19048).

Kitada S, Kress CL, Krajewska M, Jia L, Pellecchia M, Reed JC. Kitada S, et al. Among authors: reed jc. Blood. 2008 Mar 15;111(6):3211-9. doi: 10.1182/blood-2007-09-113647. Epub 2008 Jan 17. Blood. 2008. PMID: 18202226 Free PMC article.

8

Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins.

Zhai D, Jin C, Shiau CW, Kitada S, Satterthwait AC, Reed JC. Zhai D, et al. Among authors: reed jc. Mol Cancer Ther. 2008 Jun;7(6):1639-46. doi: 10.1158/1535-7163.MCT-07-2373. Mol Cancer Ther. 2008. PMID: 18566235 Free PMC article.

9

Synthesis and evaluation of Apogossypol atropisomers as potential Bcl-xL antagonists.

Wei J, Rega MF, Kitada S, Yuan H, Zhai D, Risbood P, Seltzman HH, Twine CE, Reed JC, Pellecchia M. Wei J, et al. Among authors: reed jc. Cancer Lett. 2009 Jan 8;273(1):107-13. doi: 10.1016/j.canlet.2008.07.031. Epub 2008 Sep 7. Cancer Lett. 2009. PMID: 18782651 Free PMC article.

10

Fragment-based design of small molecule X-linked inhibitor of apoptosis protein inhibitors.

Huang JW, Zhang Z, Wu B, Cellitti JF, Zhang X, Dahl R, Shiau CW, Welsh K, Emdadi A, Stebbins JL, Reed JC, Pellecchia M. Huang JW, et al. Among authors: reed jc. J Med Chem. 2008 Nov 27;51(22):7111-8. doi: 10.1021/jm8006992. J Med Chem. 2008. PMID: 18956862 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

1,003 results

Search Page

Filters