Kwon HJ - Search Results

1

Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis.

Kim CW, Moon YA, Park SW, Cheng D, Kwon HJ, Horton JD. Kim CW, et al. Among authors: kwon hj. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9626-31. doi: 10.1073/pnas.1001292107. Epub 2010 May 10. Proc Natl Acad Sci U S A. 2010. PMID: 20457939 Free PMC article.

2

Crystal structure of Spot 14, a modulator of fatty acid synthesis.

Colbert CL, Kim CW, Moon YA, Henry L, Palnitkar M, McKean WB, Fitzgerald K, Deisenhofer J, Horton JD, Kwon HJ. Colbert CL, et al. Among authors: kwon hj. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18820-5. doi: 10.1073/pnas.1012736107. Epub 2010 Oct 15. Proc Natl Acad Sci U S A. 2010. PMID: 20952656 Free PMC article.

3

Molecular basis for LDL receptor recognition by PCSK9.

Kwon HJ, Lagace TA, McNutt MC, Horton JD, Deisenhofer J. Kwon HJ, et al. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1820-5. doi: 10.1073/pnas.0712064105. Epub 2008 Feb 4. Proc Natl Acad Sci U S A. 2008. PMID: 18250299 Free PMC article.

4

Antagonism of secreted PCSK9 increases low density lipoprotein receptor expression in HepG2 cells.

McNutt MC, Kwon HJ, Chen C, Chen JR, Horton JD, Lagace TA. McNutt MC, et al. Among authors: kwon hj. J Biol Chem. 2009 Apr 17;284(16):10561-70. doi: 10.1074/jbc.M808802200. Epub 2009 Feb 17. J Biol Chem. 2009. PMID: 19224862 Free PMC article.

5

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig.

Radhakrishnan A, Ikeda Y, Kwon HJ, Brown MS, Goldstein JL. Radhakrishnan A, et al. Among authors: kwon hj. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6511-8. doi: 10.1073/pnas.0700899104. Epub 2007 Apr 11. Proc Natl Acad Sci U S A. 2007. PMID: 17428920 Free PMC article.

6

NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes.

Infante RE, Wang ML, Radhakrishnan A, Kwon HJ, Brown MS, Goldstein JL. Infante RE, et al. Among authors: kwon hj. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15287-92. doi: 10.1073/pnas.0807328105. Epub 2008 Sep 4. Proc Natl Acad Sci U S A. 2008. PMID: 18772377 Free PMC article.

7

Identification of luminal Loop 1 of Scap protein as the sterol sensor that maintains cholesterol homeostasis.

Motamed M, Zhang Y, Wang ML, Seemann J, Kwon HJ, Goldstein JL, Brown MS. Motamed M, et al. Among authors: kwon hj. J Biol Chem. 2011 May 20;286(20):18002-12. doi: 10.1074/jbc.M111.238311. Epub 2011 Mar 24. J Biol Chem. 2011. PMID: 21454655 Free PMC article.

8

Identification of surface residues on Niemann-Pick C2 essential for hydrophobic handoff of cholesterol to NPC1 in lysosomes.

Wang ML, Motamed M, Infante RE, Abi-Mosleh L, Kwon HJ, Brown MS, Goldstein JL. Wang ML, et al. Among authors: kwon hj. Cell Metab. 2010 Aug 4;12(2):166-73. doi: 10.1016/j.cmet.2010.05.016. Cell Metab. 2010. PMID: 20674861 Free PMC article.

9

Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain.

Radhakrishnan A, Sun LP, Kwon HJ, Brown MS, Goldstein JL. Radhakrishnan A, et al. Among authors: kwon hj. Mol Cell. 2004 Jul 23;15(2):259-68. doi: 10.1016/j.molcel.2004.06.019. Mol Cell. 2004. PMID: 15260976 Free article.

10

Structure of N-terminal domain of NPC1 reveals distinct subdomains for binding and transfer of cholesterol.

Kwon HJ, Abi-Mosleh L, Wang ML, Deisenhofer J, Goldstein JL, Brown MS, Infante RE. Kwon HJ, et al. Cell. 2009 Jun 26;137(7):1213-24. doi: 10.1016/j.cell.2009.03.049. Cell. 2009. PMID: 19563754 Free PMC article.

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