Dömling A - Search Results

1

1,4-Thienodiazepine-2,5-diones via MCR (I): synthesis, virtual space and p53-Mdm2 activity.

Huang Y, Wolf S, Bista M, Meireles L, Camacho C, Holak TA, Dömling A. Huang Y, et al. Among authors: domling a. Chem Biol Drug Des. 2010 Aug;76(2):116-29. doi: 10.1111/j.1747-0285.2010.00989.x. Epub 2010 May 18. Chem Biol Drug Des. 2010. PMID: 20492448 Free PMC article.

2

Small molecular weight protein-protein interaction antagonists: an insurmountable challenge?

Dömling A. Dömling A. Curr Opin Chem Biol. 2008 Jun;12(3):281-91. doi: 10.1016/j.cbpa.2008.04.603. Epub 2008 May 21. Curr Opin Chem Biol. 2008. PMID: 18501203 Review.

3

Robust NMR screening for lead compounds using tryptophan-containing proteins.

Bista M, Kowalska K, Janczyk W, Dömling A, Holak TA. Bista M, et al. Among authors: domling a. J Am Chem Soc. 2009 Jun 10;131(22):7500-1. doi: 10.1021/ja901863h. J Am Chem Soc. 2009. PMID: 19422216

4

Rapid and efficient hydrophilicity tuning of p53/mdm2 antagonists.

Srivastava S, Beck B, Wang W, Czarna A, Holak TA, Dömling A. Srivastava S, et al. Among authors: domling a. J Comb Chem. 2009 Jul-Aug;11(4):631-9. doi: 10.1021/cc9000218. J Comb Chem. 2009. PMID: 19548636 Free PMC article.

5

Efficient and diverse synthesis of indole derivatives.

Liu H, Dömling A. Liu H, et al. Among authors: domling a. J Org Chem. 2009 Sep 4;74(17):6895-8. doi: 10.1021/jo900986z. J Org Chem. 2009. PMID: 19663394

6

Cyanoacetamide multicomponent reaction (I): Parallel synthesis of cyanoacetamides.

Wang K, Nguyen K, Huang Y, Dömling A. Wang K, et al. Among authors: domling a. J Comb Chem. 2009 Sep-Oct;11(5):920-7. doi: 10.1021/cc9000778. J Comb Chem. 2009. PMID: 19694451

7

One-pot synthesis of highly functionalized seleno amino acid derivatives.

Liu H, Dömling A. Liu H, et al. Among authors: domling a. Chem Biol Drug Des. 2009 Sep;74(3):302-8. doi: 10.1111/j.1747-0285.2009.00854.x. Chem Biol Drug Des. 2009. PMID: 19703033

8

Polycyclic indole alkaloid-type compounds by MCR.

Wang W, Herdtweck E, Dömling A. Wang W, et al. Among authors: domling a. Chem Commun (Camb). 2010 Feb 7;46(5):770-2. doi: 10.1039/b917660h. Epub 2009 Dec 11. Chem Commun (Camb). 2010. PMID: 20087515

9

The Gewald multicomponent reaction.

Huang Y, Dömling A. Huang Y, et al. Among authors: domling a. Mol Divers. 2011 Feb;15(1):3-33. doi: 10.1007/s11030-010-9229-6. Epub 2010 Feb 27. Mol Divers. 2011. PMID: 20191319 Review.

10

Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery.

Popowicz GM, Czarna A, Wolf S, Wang K, Wang W, Dömling A, Holak TA. Popowicz GM, et al. Among authors: domling a. Cell Cycle. 2010 Mar 15;9(6):1104-11. doi: 10.4161/cc.9.6.10956. Epub 2010 Mar 15. Cell Cycle. 2010. PMID: 20237429

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