Sambucetti L - Search Results

1

A novel steroidal inhibitor of estrogen-related receptor alpha (ERR alpha).

Duellman SJ, Calaoagan JM, Sato BG, Fine R, Klebansky B, Chao WR, Hobbs P, Collins N, Sambucetti L, Laderoute KR. Duellman SJ, et al. Among authors: sambucetti l. Biochem Pharmacol. 2010 Sep 15;80(6):819-26. doi: 10.1016/j.bcp.2010.05.024. Epub 2010 May 31. Biochem Pharmacol. 2010. PMID: 20513360 Free PMC article.

2

SR16388: a steroidal antiangiogenic agent with potent inhibitory effect on tumor growth in vivo.

Chao WR, Amin K, Shi Y, Hobbs P, Tanabe M, Tanga M, Jong L, Collins N, Peters R, Laderoute K, Dinh D, Yean D, Hou C, Sato B, Alt C, Sambucetti L. Chao WR, et al. Among authors: sambucetti l. Angiogenesis. 2011 Mar;14(1):1-16. doi: 10.1007/s10456-010-9191-z. Epub 2010 Nov 21. Angiogenesis. 2011. PMID: 21104121

3

5'-AMP-activated protein kinase (AMPK) supports the growth of aggressive experimental human breast cancer tumors.

Laderoute KR, Calaoagan JM, Chao WR, Dinh D, Denko N, Duellman S, Kalra J, Liu X, Papandreou I, Sambucetti L, Boros LG. Laderoute KR, et al. Among authors: sambucetti l. J Biol Chem. 2014 Aug 15;289(33):22850-22864. doi: 10.1074/jbc.M114.576371. Epub 2014 Jul 3. J Biol Chem. 2014. PMID: 24993821 Free PMC article.

4

The metal-responsive transcription factor-1 protein is elevated in human tumors.

Shi Y, Amin K, Sato BG, Samuelsson SJ, Sambucetti L, Haroon ZA, Laderoute K, Murphy BJ. Shi Y, et al. Among authors: sambucetti l. Cancer Biol Ther. 2010 Mar 15;9(6):469-76. doi: 10.4161/cbt.9.6.10979. Epub 2010 Mar 20. Cancer Biol Ther. 2010. PMID: 20087061 Free PMC article.

5

An exon skipping screen identifies antitumor drugs that are potent modulators of pre-mRNA splicing, suggesting new therapeutic applications.

Shi Y, Bray W, Smith AJ, Zhou W, Calaoagan J, Lagisetti C, Sambucetti L, Crews P, Lokey RS, Webb TR. Shi Y, et al. Among authors: sambucetti l. PLoS One. 2020 May 29;15(5):e0233672. doi: 10.1371/journal.pone.0233672. eCollection 2020. PLoS One. 2020. PMID: 32469945 Free PMC article.

6

Mega-High-Throughput Screening Platform for the Discovery of Biologically Relevant Sequence-Defined Non-Natural Polymers.

Avital-Shmilovici M, Liu X, Shaler T, Lowenthal A, Bourbon P, Snider J, Tambo-Ong A, Repellin C, Yniguez K, Sambucetti L, Madrid PB, Collins N. Avital-Shmilovici M, et al. Among authors: sambucetti l. ACS Cent Sci. 2022 Jan 26;8(1):86-101. doi: 10.1021/acscentsci.1c01041. Epub 2022 Jan 11. ACS Cent Sci. 2022. PMID: 35106376 Free PMC article.

7

Pharmacodynamic assays to facilitate preclinical and clinical development of pre-mRNA splicing modulatory drug candidates.

Shi Y, Joyner AS, Shadrick W, Palacios G, Lagisetti C, Potter PM, Sambucetti LC, Stamm S, Webb TR. Shi Y, et al. Pharmacol Res Perspect. 2015 Aug;3(4):e00158. doi: 10.1002/prp2.158. Epub 2015 Jun 26. Pharmacol Res Perspect. 2015. PMID: 26171237 Free PMC article.

8

Antitumor efficacy and molecular mechanism of TLK58747, a novel DNA-alkylating prodrug.

Xu H, Wang Z, Donaldson JC, Yao H, Zhou S, Kelson AB, Ma W, Weber KT, Laborde E, Cheng M, Sambucetti L, Keck JG. Xu H, et al. Among authors: sambucetti l. Anticancer Res. 2009 Oct;29(10):3845-55. Anticancer Res. 2009. PMID: 19846918 Free article.

9

A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models.

Spangler B, Fontaine SD, Shi Y, Sambucetti L, Mattis AN, Hann B, Wells JA, Renslo AR. Spangler B, et al. Among authors: sambucetti l. J Med Chem. 2016 Dec 22;59(24):11161-11170. doi: 10.1021/acs.jmedchem.6b01470. Epub 2016 Dec 12. J Med Chem. 2016. PMID: 27936709 Free PMC article.

10

A triple exon-skipping luciferase reporter assay identifies a new CLK inhibitor pharmacophore.

Shi Y, Park J, Lagisetti C, Zhou W, Sambucetti LC, Webb TR. Shi Y, et al. Among authors: sambucetti lc. Bioorg Med Chem Lett. 2017 Feb 1;27(3):406-412. doi: 10.1016/j.bmcl.2016.12.056. Epub 2016 Dec 24. Bioorg Med Chem Lett. 2017. PMID: 28049589 Free PMC article.

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