Edelmann W - Search Results

1

MSH2/MSH6 complex promotes error-free repair of AID-induced dU:G mispairs as well as error-prone hypermutation of A:T sites.

Roa S, Li Z, Peled JU, Zhao C, Edelmann W, Scharff MD. Roa S, et al. Among authors: edelmann w. PLoS One. 2010 Jun 17;5(6):e11182. doi: 10.1371/journal.pone.0011182. PLoS One. 2010. PMID: 20567595 Free PMC article.

2

Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification.

Li Z, Scherer SJ, Ronai D, Iglesias-Ussel MD, Peled JU, Bardwell PD, Zhuang M, Lee K, Martin A, Edelmann W, Scharff MD. Li Z, et al. Among authors: edelmann w. J Exp Med. 2004 Jul 5;200(1):47-59. doi: 10.1084/jem.20040355. J Exp Med. 2004. PMID: 15238604 Free PMC article.

3

The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus.

Li Z, Zhao C, Iglesias-Ussel MD, Polonskaya Z, Zhuang M, Yang G, Luo Z, Edelmann W, Scharff MD. Li Z, et al. Among authors: edelmann w. Immunity. 2006 Apr;24(4):393-403. doi: 10.1016/j.immuni.2006.02.011. Immunity. 2006. PMID: 16618598 Free article.

4

PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance.

van Oers JM, Roa S, Werling U, Liu Y, Genschel J, Hou H Jr, Sellers RS, Modrich P, Scharff MD, Edelmann W. van Oers JM, et al. Among authors: edelmann w. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13384-9. doi: 10.1073/pnas.1008589107. Epub 2010 Jul 12. Proc Natl Acad Sci U S A. 2010. PMID: 20624957 Free PMC article.

5

Msh6 protects mature B cells from lymphoma by preserving genomic stability.

Peled JU, Sellers RS, Iglesias-Ussel MD, Shin DM, Montagna C, Zhao C, Li Z, Edelmann W, Morse HC 3rd, Scharff MD. Peled JU, et al. Among authors: edelmann w. Am J Pathol. 2010 Nov;177(5):2597-608. doi: 10.2353/ajpath.2010.100234. Epub 2010 Oct 7. Am J Pathol. 2010. PMID: 20934970 Free PMC article.

6

Mismatch-mediated error prone repair at the immunoglobulin genes.

Chahwan R, Edelmann W, Scharff MD, Roa S. Chahwan R, et al. Among authors: edelmann w. Biomed Pharmacother. 2011 Dec;65(8):529-36. doi: 10.1016/j.biopha.2011.09.001. Epub 2011 Oct 24. Biomed Pharmacother. 2011. PMID: 22100214 Free PMC article. Review.

7

The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination.

Chahwan R, van Oers JM, Avdievich E, Zhao C, Edelmann W, Scharff MD, Roa S. Chahwan R, et al. Among authors: edelmann w. J Exp Med. 2012 Apr 9;209(4):671-8. doi: 10.1084/jem.20111531. Epub 2012 Mar 26. J Exp Med. 2012. PMID: 22451719 Free PMC article.

8

AIDing antibody diversity by error-prone mismatch repair.

Chahwan R, Edelmann W, Scharff MD, Roa S. Chahwan R, et al. Among authors: edelmann w. Semin Immunol. 2012 Aug;24(4):293-300. doi: 10.1016/j.smim.2012.05.005. Epub 2012 Jun 14. Semin Immunol. 2012. PMID: 22703640 Free PMC article. Review.

9

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern.

Wiesendanger M, Kneitz B, Edelmann W, Scharff MD. Wiesendanger M, et al. Among authors: edelmann w. J Exp Med. 2000 Feb 7;191(3):579-84. doi: 10.1084/jem.191.3.579. J Exp Med. 2000. PMID: 10662804 Free PMC article.

10

Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice.

Bardwell PD, Woo CJ, Wei K, Li Z, Martin A, Sack SZ, Parris T, Edelmann W, Scharff MD. Bardwell PD, et al. Among authors: edelmann w. Nat Immunol. 2004 Feb;5(2):224-9. doi: 10.1038/ni1031. Epub 2004 Jan 11. Nat Immunol. 2004. PMID: 14716311

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