Brady SF - Search Results

1

Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.

Kim JH, Feng Z, Bauer JD, Kallifidas D, Calle PY, Brady SF. Kim JH, et al. Among authors: brady sf. Biopolymers. 2010 Sep;93(9):833-44. doi: 10.1002/bip.21450. Biopolymers. 2010. PMID: 20577994 Free PMC article.

2

Construction of soil environmental DNA cosmid libraries and screening for clones that produce biologically active small molecules.

Brady SF. Brady SF. Nat Protoc. 2007;2(5):1297-305. doi: 10.1038/nprot.2007.195. Nat Protoc. 2007. PMID: 17546026

3

Natural products from isnA-containing biosynthetic gene clusters recovered from the genomes of cultured and uncultured bacteria.

Brady SF, Bauer JD, Clarke-Pearson MF, Daniels R. Brady SF, et al. J Am Chem Soc. 2007 Oct 10;129(40):12102-3. doi: 10.1021/ja075492v. Epub 2007 Sep 19. J Am Chem Soc. 2007. PMID: 17880089 No abstract available.

4

Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.

Banik JJ, Brady SF. Banik JJ, et al. Among authors: brady sf. Proc Natl Acad Sci U S A. 2008 Nov 11;105(45):17273-7. doi: 10.1073/pnas.0807564105. Epub 2008 Nov 5. Proc Natl Acad Sci U S A. 2008. PMID: 18987322 Free PMC article.

5

An environmental DNA-derived type II polyketide biosynthetic pathway encodes the biosynthesis of the pentacyclic polyketide erdacin.

King RW, Bauer JD, Brady SF. King RW, et al. Among authors: brady sf. Angew Chem Int Ed Engl. 2009;48(34):6257-61. doi: 10.1002/anie.200901209. Angew Chem Int Ed Engl. 2009. PMID: 19621341 Free PMC article.

6

Metagenomic approaches to natural products from free-living and symbiotic organisms.

Brady SF, Simmons L, Kim JH, Schmidt EW. Brady SF, et al. Nat Prod Rep. 2009 Nov;26(11):1488-503. doi: 10.1039/b817078a. Epub 2009 Sep 16. Nat Prod Rep. 2009. PMID: 19844642 Free PMC article. Review.

7

Expanding small-molecule functional metagenomics through parallel screening of broad-host-range cosmid environmental DNA libraries in diverse proteobacteria.

Craig JW, Chang FY, Kim JH, Obiajulu SC, Brady SF. Craig JW, et al. Among authors: brady sf. Appl Environ Microbiol. 2010 Mar;76(5):1633-41. doi: 10.1128/AEM.02169-09. Epub 2010 Jan 15. Appl Environ Microbiol. 2010. PMID: 20081001 Free PMC article.

8

Utahmycins a and B, azaquinones produced by an environmental DNA clone.

Bauer JD, King RW, Brady SF. Bauer JD, et al. Among authors: brady sf. J Nat Prod. 2010 May 28;73(5):976-9. doi: 10.1021/np900786s. J Nat Prod. 2010. PMID: 20387794 Free PMC article.

9

Fluostatins produced by the heterologous expression of a TAR reassembled environmental DNA derived type II PKS gene cluster.

Feng Z, Kim JH, Brady SF. Feng Z, et al. Among authors: brady sf. J Am Chem Soc. 2010 Sep 1;132(34):11902-3. doi: 10.1021/ja104550p. J Am Chem Soc. 2010. PMID: 20690632 Free PMC article.

10

Recent application of metagenomic approaches toward the discovery of antimicrobials and other bioactive small molecules.

Banik JJ, Brady SF. Banik JJ, et al. Among authors: brady sf. Curr Opin Microbiol. 2010 Oct;13(5):603-9. doi: 10.1016/j.mib.2010.08.012. Epub 2010 Sep 29. Curr Opin Microbiol. 2010. PMID: 20884282 Free PMC article. Review.

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