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A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors.
Loboda A, Nebozhyn M, Klinghoffer R, Frazier J, Chastain M, Arthur W, Roberts B, Zhang T, Chenard M, Haines B, Andersen J, Nagashima K, Paweletz C, Lynch B, Feldman I, Dai H, Huang P, Watters J. Loboda A, et al. Among authors: dai h. BMC Med Genomics. 2010 Jun 30;3:26. doi: 10.1186/1755-8794-3-26. BMC Med Genomics. 2010. PMID: 20591134 Free PMC article.
EMT is the dominant program in human colon cancer.
Loboda A, Nebozhyn MV, Watters JW, Buser CA, Shaw PM, Huang PS, Van't Veer L, Tollenaar RA, Jackson DB, Agrawal D, Dai H, Yeatman TJ. Loboda A, et al. Among authors: dai h. BMC Med Genomics. 2011 Jan 20;4:9. doi: 10.1186/1755-8794-4-9. BMC Med Genomics. 2011. PMID: 21251323 Free PMC article.
Diurnal variation of the human adipose transcriptome and the link to metabolic disease.
Loboda A, Kraft WK, Fine B, Joseph J, Nebozhyn M, Zhang C, He Y, Yang X, Wright C, Morris M, Chalikonda I, Ferguson M, Emilsson V, Leonardson A, Lamb J, Dai H, Schadt E, Greenberg HE, Lum PY. Loboda A, et al. Among authors: dai h. BMC Med Genomics. 2009 Feb 9;2:7. doi: 10.1186/1755-8794-2-7. BMC Med Genomics. 2009. PMID: 19203388 Free PMC article.
Clinicopathologic and gene expression parameters predict liver cancer prognosis.
Hao K, Lamb J, Zhang C, Xie T, Wang K, Zhang B, Chudin E, Lee NP, Mao M, Zhong H, Greenawalt D, Ferguson MD, Ng IO, Sham PC, Poon RT, Molony C, Schadt EE, Dai H, Luk JM. Hao K, et al. Among authors: dai h. BMC Cancer. 2011 Nov 9;11:481. doi: 10.1186/1471-2407-11-481. BMC Cancer. 2011. PMID: 22070665 Free PMC article.
Genomic landscape and genetic heterogeneity in gastric adenocarcinoma revealed by whole-genome sequencing.
Wong SS, Kim KM, Ting JC, Yu K, Fu J, Liu S, Cristescu R, Nebozhyn M, Gong L, Yue YG, Wang J, Ronghua C, Loboda A, Hardwick J, Liu X, Dai H, Jin JG, Ye XS, Kang SY, Do IG, Park JO, Sohn TS, Reinhard C, Lee J, Kim S, Aggarwal A. Wong SS, et al. Among authors: dai h. Nat Commun. 2014 Nov 19;5:5477. doi: 10.1038/ncomms6477. Nat Commun. 2014. PMID: 25407104 Free article.
Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting.
Lamb JR, Zhang C, Xie T, Wang K, Zhang B, Hao K, Chudin E, Fraser HB, Millstein J, Ferguson M, Suver C, Ivanovska I, Scott M, Philippar U, Bansal D, Zhang Z, Burchard J, Smith R, Greenawalt D, Cleary M, Derry J, Loboda A, Watters J, Poon RT, Fan ST, Yeung C, Lee NP, Guinney J, Molony C, Emilsson V, Buser-Doepner C, Zhu J, Friend S, Mao M, Shaw PM, Dai H, Luk JM, Schadt EE. Lamb JR, et al. Among authors: dai h. PLoS One. 2011;6(7):e20090. doi: 10.1371/journal.pone.0020090. Epub 2011 Jul 5. PLoS One. 2011. PMID: 21750698 Free PMC article.
Genome-wide identification of RNA editing in hepatocellular carcinoma.
Kang L, Liu X, Gong Z, Zheng H, Wang J, Li Y, Yang H, Hardwick J, Dai H, Poon RT, Lee NP, Mao M, Peng Z, Chen R. Kang L, et al. Among authors: dai h. Genomics. 2015 Feb;105(2):76-82. doi: 10.1016/j.ygeno.2014.11.005. Epub 2014 Nov 25. Genomics. 2015. PMID: 25462863 Free article.
6,593 results