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A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair.
Kadyrov FA, Genschel J, Fang Y, Penland E, Edelmann W, Modrich P. Kadyrov FA, et al. Among authors: modrich p. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8495-500. doi: 10.1073/pnas.0903654106. Epub 2009 May 6. Proc Natl Acad Sci U S A. 2009. PMID: 19420220 Free PMC article.
Functions of MutLalpha, replication protein A (RPA), and HMGB1 in 5'-directed mismatch repair.
Genschel J, Modrich P. Genschel J, et al. Among authors: modrich p. J Biol Chem. 2009 Aug 7;284(32):21536-44. doi: 10.1074/jbc.M109.021287. Epub 2009 Jun 10. J Biol Chem. 2009. PMID: 19515846 Free PMC article.
One model attributes the primary termination function in this system to RPA, with MutLalpha functioning in a secondary capacity by suppressing Exo1 hydrolysis of mismatch-free DNA (Genschel, J., and Modrich, P. (2003) Mol. Cell 12, 1077-1086). A second invokes MutLa …
One model attributes the primary termination function in this system to RPA, with MutLalpha functioning in a secondary capacity by suppressi …
Human exonuclease I is required for 5' and 3' mismatch repair.
Genschel J, Bazemore LR, Modrich P. Genschel J, et al. Among authors: modrich p. J Biol Chem. 2002 Apr 12;277(15):13302-11. doi: 10.1074/jbc.M111854200. Epub 2002 Jan 24. J Biol Chem. 2002. PMID: 11809771 Free article.
180 results