Giuliano KA - Search Results

1

Implementation of a 220,000-compound HCS campaign to identify disruptors of the interaction between p53 and hDM2 and characterization of the confirmed hits.

Dudgeon DD, Shinde S, Hua Y, Shun TY, Lazo JS, Strock CJ, Giuliano KA, Taylor DL, Johnston PA, Johnston PA. Dudgeon DD, et al. Among authors: giuliano ka. J Biomol Screen. 2010 Aug;15(7):766-82. doi: 10.1177/1087057110375304. Epub 2010 Jul 16. J Biomol Screen. 2010. PMID: 20639499

2

Cellular systems biology profiling applied to cellular models of disease.

Giuliano KA, Premkumar DR, Strock CJ, Johnston P, Taylor L. Giuliano KA, et al. Comb Chem High Throughput Screen. 2009 Nov;12(9):838-48. doi: 10.2174/138620709789383286. Comb Chem High Throughput Screen. 2009. PMID: 19531002

3

Early safety assessment using cellular systems biology yields insights into mechanisms of action.

Giuliano KA, Gough AH, Taylor DL, Vernetti LA, Johnston PA. Giuliano KA, et al. J Biomol Screen. 2010 Aug;15(7):783-97. doi: 10.1177/1087057110376413. Epub 2010 Jul 16. J Biomol Screen. 2010. PMID: 20639501

4

Characterization and optimization of a novel protein-protein interaction biosensor high-content screening assay to identify disruptors of the interactions between p53 and hDM2.

Dudgeon DD, Shinde SN, Shun TY, Lazo JS, Strock CJ, Giuliano KA, Taylor DL, Johnston PA, Johnston PA. Dudgeon DD, et al. Among authors: giuliano ka. Assay Drug Dev Technol. 2010 Aug;8(4):437-58. doi: 10.1089/adt.2010.0281. Assay Drug Dev Technol. 2010. PMID: 20662736 Free PMC article.

5

High-content screening with siRNA optimizes a cell biological approach to drug discovery: defining the role of P53 activation in the cellular response to anticancer drugs.

Giuliano KA, Chen YT, Taylor DL. Giuliano KA, et al. J Biomol Screen. 2004 Oct;9(7):557-68. doi: 10.1177/1087057104265387. J Biomol Screen. 2004. PMID: 15475475

6

Reagents to measure and manipulate cell functions.

Giuliano KA, Taylor DL, Waggoner AS. Giuliano KA, et al. Methods Mol Biol. 2007;356:141-63. doi: 10.1385/1-59745-217-3:141. Methods Mol Biol. 2007. PMID: 16988401

7

Systems cell biology based on high-content screening.

Giuliano KA, Johnston PA, Gough A, Taylor DL. Giuliano KA, et al. Methods Enzymol. 2006;414:601-19. doi: 10.1016/S0076-6879(06)14031-8. Methods Enzymol. 2006. PMID: 17110213 Review.

8

Multiplexed high content screening assays create a systems cell biology approach to drug discovery.

Taylor DL, Giuliano KA. Taylor DL, et al. Among authors: giuliano ka. Drug Discov Today. 2005 Autumn;Suppl:13-8. Drug Discov Today. 2005. PMID: 23570162

9

Multiplexed high content screening assays create a systems cell biology approach to drug discovery.

Taylor DL, Giuliano KA. Taylor DL, et al. Among authors: giuliano ka. Drug Discov Today Technol. 2005 Summer;2(2):149-54. doi: 10.1016/j.ddtec.2005.05.023. Drug Discov Today Technol. 2005. PMID: 24981842

10

Fluorescent-protein biosensors: new tools for drug discovery.

Giuliano KA, Taylor DL. Giuliano KA, et al. Trends Biotechnol. 1998 Mar;16(3):135-40. doi: 10.1016/S0167-7799(97)01166-9. Trends Biotechnol. 1998. PMID: 9523461 Review.

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