Hua Y - Search Results

1

Implementation of a 220,000-compound HCS campaign to identify disruptors of the interaction between p53 and hDM2 and characterization of the confirmed hits.

Dudgeon DD, Shinde S, Hua Y, Shun TY, Lazo JS, Strock CJ, Giuliano KA, Taylor DL, Johnston PA, Johnston PA. Dudgeon DD, et al. Among authors: hua y. J Biomol Screen. 2010 Aug;15(7):766-82. doi: 10.1177/1087057110375304. Epub 2010 Jul 16. J Biomol Screen. 2010. PMID: 20639499

2

Development and validation of a high-content screening assay to identify inhibitors of cytoplasmic dynein-mediated transport of glucocorticoid receptor to the nucleus.

Johnston PA, Shinde SN, Hua Y, Shun TY, Lazo JS, Day BW. Johnston PA, et al. Among authors: hua y. Assay Drug Dev Technol. 2012 Oct;10(5):432-56. doi: 10.1089/adt.2012.456. Epub 2012 Jul 25. Assay Drug Dev Technol. 2012. PMID: 22830992 Free PMC article.

3

High-content pSTAT3/1 imaging assays to screen for selective inhibitors of STAT3 pathway activation in head and neck cancer cell lines.

Johnston PA, Sen M, Hua Y, Camarco D, Shun TY, Lazo JS, Grandis JR. Johnston PA, et al. Among authors: hua y. Assay Drug Dev Technol. 2014 Jan-Feb;12(1):55-79. doi: 10.1089/adt.2013.524. Epub 2013 Oct 15. Assay Drug Dev Technol. 2014. PMID: 24127660 Free PMC article.

4

High-content positional biosensor screening assay for compounds to prevent or disrupt androgen receptor and transcriptional intermediary factor 2 protein-protein interactions.

Hua Y, Shun TY, Strock CJ, Johnston PA. Hua Y, et al. Assay Drug Dev Technol. 2014 Sep;12(7):395-418. doi: 10.1089/adt.2014.594. Assay Drug Dev Technol. 2014. PMID: 25181412 Free PMC article.

5

2-Guanidinoquinazolines as new inhibitors of the STAT3 pathway.

LaPorte MG, da Paz Lima DJ, Zhang F, Sen M, Grandis JR, Camarco D, Hua Y, Johnston PA, Lazo JS, Resnick LO, Wipf P, Huryn DM. LaPorte MG, et al. Among authors: hua y. Bioorg Med Chem Lett. 2014 Nov 1;24(21):5081-5. doi: 10.1016/j.bmcl.2014.09.001. Epub 2014 Sep 15. Bioorg Med Chem Lett. 2014. PMID: 25288188 Free PMC article.

6

High content screening biosensor assay to identify disruptors of p53-hDM2 protein-protein interactions.

Hua Y, Strock CJ, Johnston PA. Hua Y, et al. Methods Mol Biol. 2015;1278:555-65. doi: 10.1007/978-1-4939-2425-7_37. Methods Mol Biol. 2015. PMID: 25859976

7

HCS campaign to identify selective inhibitors of IL-6-induced STAT3 pathway activation in head and neck cancer cell lines.

Johnston PA, Sen M, Hua Y, Camarco DP, Shun TY, Lazo JS, Wilson GM, Resnick LO, LaPorte MG, Wipf P, Huryn DM, Grandis JR. Johnston PA, et al. Among authors: hua y. Assay Drug Dev Technol. 2015 Sep;13(7):356-76. doi: 10.1089/adt.2015.663. Assay Drug Dev Technol. 2015. PMID: 26317883 Free PMC article.

8

Development and Implementation of a High-Throughput High-Content Screening Assay to Identify Inhibitors of Androgen Receptor Nuclear Localization in Castration-Resistant Prostate Cancer Cells.

Johnston PA, Nguyen MM, Dar JA, Ai J, Wang Y, Masoodi KZ, Shun T, Shinde S, Camarco DP, Hua Y, Huryn DM, Wilson GM, Lazo JS, Nelson JB, Wipf P, Wang Z. Johnston PA, et al. Among authors: hua y. Assay Drug Dev Technol. 2016 May;14(4):226-39. doi: 10.1089/adt.2016.716. Assay Drug Dev Technol. 2016. PMID: 27187604 Free PMC article.

9

Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors.

LaPorte MG, Wang Z, Colombo R, Garzan A, Peshkov VA, Liang M, Johnston PA, Schurdak ME, Sen M, Camarco DP, Hua Y, Pollock NI, Lazo JS, Grandis JR, Wipf P, Huryn DM. LaPorte MG, et al. Among authors: hua y. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3581-5. doi: 10.1016/j.bmcl.2016.06.017. Epub 2016 Jun 9. Bioorg Med Chem Lett. 2016. PMID: 27381083 Free PMC article.

10

Reconfiguring the AR-TIF2 Protein-Protein Interaction HCS Assay in Prostate Cancer Cells and Characterizing the Hits from a LOPAC Screen.

Fancher AT, Hua Y, Camarco DP, Close DA, Strock CJ, Johnston PA. Fancher AT, et al. Among authors: hua y. Assay Drug Dev Technol. 2016 Oct;14(8):453-477. doi: 10.1089/adt.2016.741. Epub 2016 Sep 8. Assay Drug Dev Technol. 2016. PMID: 27606620 Free PMC article.

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