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Docosahexaenoic acid promotes oligodendrocyte differentiation via PPAR-γ signalling and prevents tumor necrosis factor-α-dependent maturational arrest.
Bernardo A, Giammarco ML, De Nuccio C, Ajmone-Cat MA, Visentin S, De Simone R, Minghetti L. Bernardo A, et al. Among authors: de simone r, de nuccio c. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Sep;1862(9):1013-1023. doi: 10.1016/j.bbalip.2017.06.014. Epub 2017 Jun 22. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28647405
Nonenzymatic oxygenated metabolites of α-linolenic acid B1- and L1-phytoprostanes protect immature neurons from oxidant injury and promote differentiation of oligodendrocyte progenitors through PPAR-γ activation.
Minghetti L, Salvi R, Lavinia Salvatori M, Ajmone-Cat MA, De Nuccio C, Visentin S, Bultel-Poncé V, Oger C, Guy A, Galano JM, Greco A, Bernardo A, Durand T. Minghetti L, et al. Among authors: de nuccio c. Free Radic Biol Med. 2014 Aug;73:41-50. doi: 10.1016/j.freeradbiomed.2014.04.025. Epub 2014 May 2. Free Radic Biol Med. 2014. PMID: 24794409
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