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Human umbilical cord blood cells transfected with VEGF and L(1)CAM do not differentiate into neurons but transform into vascular endothelial cells and secrete neuro-trophic factors to support neuro-genesis-a novel approach in stem cell therapy.
Rizvanov AA, Kiyasov AP, Gaziziov IM, Yilmaz TS, Kaligin MS, Andreeva DI, Shafigullina AK, Guseva DS, Kiselev SL, Matin K, Palotás A, Islamov RR. Rizvanov AA, et al. Neurochem Int. 2008 Dec;53(6-8):389-94. doi: 10.1016/j.neuint.2008.09.011. Epub 2008 Sep 26. Neurochem Int. 2008. PMID: 18948156
Genetically modified human umbilical cord blood cells expressing vascular endothelial growth factor and fibroblast growth factor 2 differentiate into glial cells after transplantation into amyotrophic lateral sclerosis transgenic mice.
Rizvanov AA, Guseva DS, Salafutdinov II, Kudryashova NV, Bashirov FV, Kiyasov AP, Yalvaç ME, Gazizov IM, Kaligin MS, Sahin F, Mukhamedyarov MA, Palotás A, Islamov RR. Rizvanov AA, et al. Exp Biol Med (Maywood). 2011 Jan;236(1):91-8. doi: 10.1258/ebm.2010.010172. Epub 2010 Dec 16. Exp Biol Med (Maywood). 2011. PMID: 21163822 Free article.
261 results