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Hepcidin and Hfe in iron overload in beta-thalassemia.
Gardenghi S, Ramos P, Follenzi A, Rao N, Rachmilewitz EA, Giardina PJ, Grady RW, Rivella S. Gardenghi S, et al. Among authors: grady rw. Ann N Y Acad Sci. 2010 Aug;1202:221-5. doi: 10.1111/j.1749-6632.2010.05595.x. Ann N Y Acad Sci. 2010. PMID: 20712796 Free PMC article. Review.
Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice.
Gardenghi S, Ramos P, Marongiu MF, Melchiori L, Breda L, Guy E, Muirhead K, Rao N, Roy CN, Andrews NC, Nemeth E, Follenzi A, An X, Mohandas N, Ginzburg Y, Rachmilewitz EA, Giardina PJ, Grady RW, Rivella S. Gardenghi S, et al. Among authors: grady rw. J Clin Invest. 2010 Dec;120(12):4466-77. doi: 10.1172/JCI41717. Epub 2010 Nov 22. J Clin Invest. 2010. PMID: 21099112 Free PMC article.
Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia.
Ramos P, Casu C, Gardenghi S, Breda L, Crielaard BJ, Guy E, Marongiu MF, Gupta R, Levine RL, Abdel-Wahab O, Ebert BL, Van Rooijen N, Ghaffari S, Grady RW, Giardina PJ, Rivella S. Ramos P, et al. Among authors: grady rw. Nat Med. 2013 Apr;19(4):437-45. doi: 10.1038/nm.3126. Epub 2013 Mar 17. Nat Med. 2013. PMID: 23502961 Free PMC article.
Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients.
Breda L, Casu C, Gardenghi S, Bianchi N, Cartegni L, Narla M, Yazdanbakhsh K, Musso M, Manwani D, Little J, Gardner LB, Kleinert DA, Prus E, Fibach E, Grady RW, Giardina PJ, Gambari R, Rivella S. Breda L, et al. Among authors: grady rw. PLoS One. 2012;7(3):e32345. doi: 10.1371/journal.pone.0032345. Epub 2012 Mar 27. PLoS One. 2012. PMID: 22479321 Free PMC article.
Changes in bone microarchitecture and biomechanical properties in the th3 thalassemia mouse are associated with decreased bone turnover and occur during the period of bone accrual.
Vogiatzi MG, Tsay J, Verdelis K, Rivella S, Grady RW, Doty S, Giardina PJ, Boskey AL. Vogiatzi MG, et al. Among authors: grady rw. Calcif Tissue Int. 2010 Jun;86(6):484-94. doi: 10.1007/s00223-010-9365-0. Epub 2010 May 7. Calcif Tissue Int. 2010. PMID: 20449578 Free PMC article.
Combined iron chelation therapy.
Galanello R, Agus A, Campus S, Danjou F, Giardina PJ, Grady RW. Galanello R, et al. Among authors: grady rw. Ann N Y Acad Sci. 2010 Aug;1202:79-86. doi: 10.1111/j.1749-6632.2010.05591.x. Ann N Y Acad Sci. 2010. PMID: 20712777
152 results