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Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis.
Guzman JD, Gupta A, Evangelopoulos D, Basavannacharya C, Pabon LC, Plazas EA, Muñoz DR, Delgado WA, Cuca LE, Ribon W, Gibbons S, Bhakta S. Guzman JD, et al. Among authors: evangelopoulos d. J Antimicrob Chemother. 2010 Oct;65(10):2101-7. doi: 10.1093/jac/dkq313. Epub 2010 Aug 18. J Antimicrob Chemother. 2010. PMID: 20719764
Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics.
Guzman JD, Wube A, Evangelopoulos D, Gupta A, Hüfner A, Basavannacharya C, Rahman MM, Thomaschitz C, Bauer R, McHugh TD, Nobeli I, Prieto JM, Gibbons S, Bucar F, Bhakta S. Guzman JD, et al. Among authors: evangelopoulos d. J Antimicrob Chemother. 2011 Aug;66(8):1766-72. doi: 10.1093/jac/dkr203. Epub 2011 May 28. J Antimicrob Chemother. 2011. PMID: 21622974 Free PMC article.
Antimycobacterials from lovage root (Ligusticum officinale Koch).
Guzman JD, Evangelopoulos D, Gupta A, Prieto JM, Gibbons S, Bhakta S. Guzman JD, et al. Among authors: evangelopoulos d. Phytother Res. 2013 Jul;27(7):993-8. doi: 10.1002/ptr.4823. Epub 2012 Aug 16. Phytother Res. 2013. PMID: 22899555
A new plant-derived antibacterial is an inhibitor of efflux pumps in Staphylococcus aureus.
Shiu WK, Malkinson JP, Rahman MM, Curry J, Stapleton P, Gunaratnam M, Neidle S, Mushtaq S, Warner M, Livermore DM, Evangelopoulos D, Basavannacharya C, Bhakta S, Schindler BD, Seo SM, Coleman D, Kaatz GW, Gibbons S. Shiu WK, et al. Among authors: evangelopoulos d. Int J Antimicrob Agents. 2013 Dec;42(6):513-8. doi: 10.1016/j.ijantimicag.2013.08.007. Epub 2013 Sep 16. Int J Antimicrob Agents. 2013. PMID: 24119569
Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase.
Guzman JD, Pesnot T, Barrera DA, Davies HM, McMahon E, Evangelopoulos D, Mortazavi PN, Munshi T, Maitra A, Lamming ED, Angell R, Gershater MC, Redmond JM, Needham D, Ward JM, Cuca LE, Hailes HC, Bhakta S. Guzman JD, et al. Among authors: evangelopoulos d. J Antimicrob Chemother. 2015;70(6):1691-703. doi: 10.1093/jac/dkv010. Epub 2015 Feb 4. J Antimicrob Chemother. 2015. PMID: 25656411 Free PMC article.
156 results