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Arachidonic acid, eicosanoids, and fracture repair.
Wixted JJ, Fanning P, Rothkopf I, Stein G, Lian J. Wixted JJ, et al. J Orthop Trauma. 2010 Sep;24(9):539-42. doi: 10.1097/BOT.0b013e3181f17b33. J Orthop Trauma. 2010. PMID: 20736790 Review.
The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss.
Pratap J, Akech J, Wixted JJ, Szabo G, Hussain S, McGee-Lawrence ME, Li X, Bedard K, Dhillon RJ, van Wijnen AJ, Stein JL, Stein GS, Westendorf JJ, Lian JB. Pratap J, et al. Among authors: wixted jj. Mol Cancer Ther. 2010 Dec;9(12):3210-20. doi: 10.1158/1535-7163.MCT-10-0572. Mol Cancer Ther. 2010. PMID: 21159607 Free PMC article.
Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions.
Akech J, Wixted JJ, Bedard K, van der Deen M, Hussain S, Guise TA, van Wijnen AJ, Stein JL, Languino LR, Altieri DC, Pratap J, Keller E, Stein GS, Lian JB. Akech J, et al. Among authors: wixted jj. Oncogene. 2010 Feb 11;29(6):811-21. doi: 10.1038/onc.2009.389. Epub 2009 Nov 16. Oncogene. 2010. PMID: 19915614 Free PMC article.
Integrin αvβ6 promotes an osteolytic program in cancer cells by upregulating MMP2.
Dutta A, Li J, Lu H, Akech J, Pratap J, Wang T, Zerlanko BJ, FitzGerald TJ, Jiang Z, Birbe R, Wixted J, Violette SM, Stein JL, Stein GS, Lian JB, Languino LR. Dutta A, et al. Cancer Res. 2014 Mar 1;74(5):1598-608. doi: 10.1158/0008-5472.CAN-13-1796. Epub 2014 Jan 2. Cancer Res. 2014. PMID: 24385215 Free PMC article.
Enhancing fracture repair: cell-based approaches.
Wixted J, Challa S, Nazarian A. Wixted J, et al. OTA Int. 2022 Mar 10;5(1 Suppl):e168. doi: 10.1097/OI9.0000000000000168. eCollection 2022 Mar. OTA Int. 2022. PMID: 35282391 Free PMC article.
44 results