Schubiger PA - Search Results

1

In vitro and in vivo characterization of novel 18F-labeled bombesin analogues for targeting GRPR-positive tumors.

Mu L, Honer M, Becaud J, Martic M, Schubiger PA, Ametamey SM, Stellfeld T, Graham K, Borkowski S, Lehmann L, Dinkelborg L, Srinivasan A. Mu L, et al. Among authors: schubiger pa. Bioconjug Chem. 2010 Oct 20;21(10):1864-71. doi: 10.1021/bc100222u. Bioconjug Chem. 2010. PMID: 20857927

2

Direct one-step 18F-labeling of peptides via nucleophilic aromatic substitution.

Becaud J, Mu L, Karramkam M, Schubiger PA, Ametamey SM, Graham K, Stellfeld T, Lehmann L, Borkowski S, Berndorff D, Dinkelborg L, Srinivasan A, Smits R, Koksch B. Becaud J, et al. Among authors: schubiger pa. Bioconjug Chem. 2009 Dec;20(12):2254-61. doi: 10.1021/bc900240z. Bioconjug Chem. 2009. PMID: 19921791

3

Structure-activity relationships of fluorinated (E)-3-((6-methylpyridin-2-yl)ethynyl)cyclohex-2-enone-O-methyloxime (ABP688) derivatives and the discovery of a high affinity analogue as a potential candidate for imaging metabotropic glutamate recepors subtype 5 (mGluR5) with positron emission tomography (PET).

Baumann CA, Mu L, Johannsen S, Honer M, Schubiger PA, Ametamey SM. Baumann CA, et al. Among authors: schubiger pa. J Med Chem. 2010 May 27;53(10):4009-17. doi: 10.1021/jm901850k. J Med Chem. 2010. PMID: 20411954

4

Syntheses and pharmacological characterization of novel thiazole derivatives as potential mGluR5 PET ligands.

Baumann CA, Mu L, Wertli N, Krämer SD, Honer M, Schubiger PA, Ametamey SM. Baumann CA, et al. Among authors: schubiger pa. Bioorg Med Chem. 2010 Aug 15;18(16):6044-54. doi: 10.1016/j.bmc.2010.06.070. Epub 2010 Jun 25. Bioorg Med Chem. 2010. PMID: 20634080

5

18F-labeled bombesin analog for specific and effective targeting of prostate tumors expressing gastrin-releasing peptide receptors.

Honer M, Mu L, Stellfeld T, Graham K, Martic M, Fischer CR, Lehmann L, Schubiger PA, Ametamey SM, Dinkelborg L, Srinivasan A, Borkowski S. Honer M, et al. Among authors: schubiger pa. J Nucl Med. 2011 Feb;52(2):270-8. doi: 10.2967/jnumed.110.081620. Epub 2011 Jan 13. J Nucl Med. 2011. PMID: 21233180 Free article.

6

In vitro and in vivo evaluation of [18F]-FDEGPECO as a PET tracer for imaging the metabotropic glutamate receptor subtype 5 (mGluR5).

Wanger-Baumann CA, Mu L, Honer M, Belli S, Alf MF, Schubiger PA, Krämer SD, Ametamey SM. Wanger-Baumann CA, et al. Among authors: schubiger pa. Neuroimage. 2011 Jun 1;56(3):984-91. doi: 10.1016/j.neuroimage.2011.03.024. Epub 2011 Mar 21. Neuroimage. 2011. PMID: 21406237

7

Radiolabeling and in vitro and in vivo evaluation of [18F]-FE-DABP688 as a PET radioligand for the metabotropic glutamate receptor subtype 5.

Honer M, Stoffel A, Kessler LJ, Schubiger PA, Ametamey SM. Honer M, et al. Among authors: schubiger pa. Nucl Med Biol. 2007 Nov;34(8):973-80. doi: 10.1016/j.nucmedbio.2007.07.017. Epub 2007 Sep 19. Nucl Med Biol. 2007. PMID: 17998101

8

Synthesis, 18F-labeling, and in vitro and in vivo studies of bombesin peptides modified with silicon-based building blocks.

Höhne A, Mu L, Honer M, Schubiger PA, Ametamey SM, Graham K, Stellfeld T, Borkowski S, Berndorff D, Klar U, Voigtmann U, Cyr JE, Friebe M, Dinkelborg L, Srinivasan A. Höhne A, et al. Among authors: schubiger pa. Bioconjug Chem. 2008 Sep;19(9):1871-9. doi: 10.1021/bc800157h. Epub 2008 Aug 28. Bioconjug Chem. 2008. PMID: 18754574

9

Fluorine-18 click radiosynthesis and preclinical evaluation of a new 18F-labeled folic acid derivative.

Ross TL, Honer M, Lam PY, Mindt TL, Groehn V, Schibli R, Schubiger PA, Ametamey SM. Ross TL, et al. Among authors: schubiger pa. Bioconjug Chem. 2008 Dec;19(12):2462-70. doi: 10.1021/bc800356r. Bioconjug Chem. 2008. PMID: 19053298

10

Design, synthesis, and initial evaluation of a high affinity positron emission tomography probe for imaging matrix metalloproteinases 2 and 9.

Selivanova SV, Stellfeld T, Heinrich TK, Müller A, Krämer SD, Schubiger PA, Schibli R, Ametamey SM, Vos B, Meding J, Bauser M, Hütter J, Dinkelborg LM. Selivanova SV, et al. Among authors: schubiger pa. J Med Chem. 2013 Jun 27;56(12):4912-20. doi: 10.1021/jm400156p. Epub 2013 Jun 7. J Med Chem. 2013. PMID: 23688254

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