Sinclair C - Search Results

1

Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells.

White AJ, Nakamura K, Jenkinson WE, Saini M, Sinclair C, Seddon B, Narendran P, Pfeffer K, Nitta T, Takahama Y, Caamano JH, Lane PJ, Jenkinson EJ, Anderson G. White AJ, et al. Among authors: sinclair c. J Immunol. 2010 Oct 15;185(8):4769-76. doi: 10.4049/jimmunol.1002151. Epub 2010 Sep 22. J Immunol. 2010. PMID: 20861360 Free PMC article.

2

Overlapping and asymmetric functions of TCR signaling during thymic selection of CD4 and CD8 lineages.

Sinclair C, Seddon B. Sinclair C, et al. J Immunol. 2014 Jun 1;192(11):5151-9. doi: 10.4049/jimmunol.1303085. Epub 2014 Apr 25. J Immunol. 2014. PMID: 24771853 Free PMC article.

3

Differential requirement for IL-2 and IL-15 during bifurcated development of thymic regulatory T cells.

Marshall D, Sinclair C, Tung S, Seddon B. Marshall D, et al. Among authors: sinclair c. J Immunol. 2014 Dec 1;193(11):5525-33. doi: 10.4049/jimmunol.1402144. Epub 2014 Oct 27. J Immunol. 2014. PMID: 25348623 Free PMC article.

4

Regulation of Zap70 expression during thymocyte development enables temporal separation of CD4 and CD8 repertoire selection at different signaling thresholds.

Saini M, Sinclair C, Marshall D, Tolaini M, Sakaguchi S, Seddon B. Saini M, et al. Among authors: sinclair c. Sci Signal. 2010 Mar 23;3(114):ra23. doi: 10.1126/scisignal.2000702. Sci Signal. 2010. PMID: 20332428

5

The long-term survival potential of mature T lymphocytes is programmed during development in the thymus.

Sinclair C, Saini M, Schim van der Loeff I, Sakaguchi S, Seddon B. Sinclair C, et al. Sci Signal. 2011 Nov 15;4(199):ra77. doi: 10.1126/scisignal.2002246. Sci Signal. 2011. PMID: 22087033

6

A Zap70-dependent feedback circuit is essential for efficient selection of CD4 lineage thymocytes.

Sinclair C, Ono M, Seddon B. Sinclair C, et al. Immunol Cell Biol. 2015 Apr;93(4):406-16. doi: 10.1038/icb.2014.107. Epub 2015 Jan 20. Immunol Cell Biol. 2015. PMID: 25601273

7

Asymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune system.

Sinclair C, Bains I, Yates AJ, Seddon B. Sinclair C, et al. Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):E2905-14. doi: 10.1073/pnas.1304859110. Epub 2013 Jul 15. Proc Natl Acad Sci U S A. 2013. PMID: 23858460 Free PMC article.

8

Induction of cytotoxic T lymphocytes with peptides in vitro: identification of candidate T-cell epitopes in human papilloma virus.

Stauss HJ, Davies H, Sadovnikova E, Chain B, Horowitz N, Sinclair C. Stauss HJ, et al. Among authors: sinclair c. Proc Natl Acad Sci U S A. 1992 Sep 1;89(17):7871-5. doi: 10.1073/pnas.89.17.7871. Proc Natl Acad Sci U S A. 1992. PMID: 1381502 Free PMC article.

9

Translating glycolytic metabolism to innate immunity in dendritic cells.

Cortese M, Sinclair C, Pulendran B. Cortese M, et al. Among authors: sinclair c. Cell Metab. 2014 May 6;19(5):737-739. doi: 10.1016/j.cmet.2014.04.012. Cell Metab. 2014. PMID: 24807219 Free PMC article.

10

mTOR regulates metabolic adaptation of APCs in the lung and controls the outcome of allergic inflammation.

Sinclair C, Bommakanti G, Gardinassi L, Loebbermann J, Johnson MJ, Hakimpour P, Hagan T, Benitez L, Todor A, Machiah D, Oriss T, Ray A, Bosinger S, Ravindran R, Li S, Pulendran B. Sinclair C, et al. Science. 2017 Sep 8;357(6355):1014-1021. doi: 10.1126/science.aaj2155. Epub 2017 Aug 10. Science. 2017. PMID: 28798047 Free PMC article.

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