Qi J - Search Results

1

The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities.

Qi J, Pellecchia M, Ronai ZA. Qi J, et al. Oncotarget. 2010 Sep;1(5):379-85. doi: 10.18632/oncotarget.171. Oncotarget. 2010. PMID: 21037926 Free PMC article. Review.

2

The ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways.

Qi J, Nakayama K, Gaitonde S, Goydos JS, Krajewski S, Eroshkin A, Bar-Sagi D, Bowtell D, Ronai Z. Qi J, et al. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16713-8. doi: 10.1073/pnas.0804063105. Epub 2008 Oct 22. Proc Natl Acad Sci U S A. 2008. PMID: 18946040 Free PMC article.

3

The ubiquitin ligase Siah2 and the hypoxia response.

Nakayama K, Qi J, Ronai Z. Nakayama K, et al. Among authors: qi j. Mol Cancer Res. 2009 Apr;7(4):443-51. doi: 10.1158/1541-7786.MCR-08-0458. Mol Cancer Res. 2009. PMID: 19372575 Free PMC article. Review.

4

Inhibition of Siah2 ubiquitin ligase by vitamin K3 (menadione) attenuates hypoxia and MAPK signaling and blocks melanoma tumorigenesis.

Shah M, Stebbins JL, Dewing A, Qi J, Pellecchia M, Ronai ZA. Shah M, et al. Among authors: qi j. Pigment Cell Melanoma Res. 2009 Dec;22(6):799-808. doi: 10.1111/j.1755-148X.2009.00628.x. Epub 2009 Aug 27. Pigment Cell Melanoma Res. 2009. PMID: 19712206 Free PMC article.

5

Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors.

Qi J, Nakayama K, Cardiff RD, Borowsky AD, Kaul K, Williams R, Krajewski S, Mercola D, Carpenter PM, Bowtell D, Ronai ZA. Qi J, et al. Cancer Cell. 2010 Jul 13;18(1):23-38. doi: 10.1016/j.ccr.2010.05.024. Cancer Cell. 2010. PMID: 20609350 Free PMC article.

6

USP13 enzyme regulates Siah2 ligase stability and activity via noncatalytic ubiquitin-binding domains.

Scortegagna M, Subtil T, Qi J, Kim H, Zhao W, Gu W, Kluger H, Ronai ZA. Scortegagna M, et al. Among authors: qi j. J Biol Chem. 2011 Aug 5;286(31):27333-41. doi: 10.1074/jbc.M111.218214. Epub 2011 Jun 9. J Biol Chem. 2011. PMID: 21659512 Free PMC article.

7

The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity.

Qi J, Tripathi M, Mishra R, Sahgal N, Fazli L, Ettinger S, Placzek WJ, Claps G, Chung LW, Bowtell D, Gleave M, Bhowmick N, Ronai ZA. Qi J, et al. Cancer Cell. 2013 Mar 18;23(3):332-46. doi: 10.1016/j.ccr.2013.02.016. Cancer Cell. 2013. PMID: 23518348 Free PMC article.

8

Regulators and effectors of Siah ubiquitin ligases.

Qi J, Kim H, Scortegagna M, Ronai ZA. Qi J, et al. Cell Biochem Biophys. 2013 Sep;67(1):15-24. doi: 10.1007/s12013-013-9636-2. Cell Biochem Biophys. 2013. PMID: 23700162 Free PMC article. Review.

9

Dysregulation of ubiquitin ligases in cancer.

Qi J, Ronai ZA. Qi J, et al. Drug Resist Updat. 2015 Nov;23:1-11. doi: 10.1016/j.drup.2015.09.001. Epub 2015 Sep 28. Drug Resist Updat. 2015. PMID: 26690337 Free PMC article. Review.

10

Ubiquitin ligases in oncogenic transformation and cancer therapy.

Senft D, Qi J, Ronai ZA. Senft D, et al. Among authors: qi j. Nat Rev Cancer. 2018 Feb;18(2):69-88. doi: 10.1038/nrc.2017.105. Epub 2017 Dec 15. Nat Rev Cancer. 2018. PMID: 29242641 Free PMC article. Review.

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