Kong Y - Search Results

1

High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition.

Awad O, Yustein JT, Shah P, Gul N, Katuri V, O'Neill A, Kong Y, Brown ML, Toretsky JA, Loeb DM. Awad O, et al. Among authors: kong y. PLoS One. 2010 Nov 11;5(11):e13943. doi: 10.1371/journal.pone.0013943. PLoS One. 2010. PMID: 21085683 Free PMC article.

2

A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma.

Erkizan HV, Kong Y, Merchant M, Schlottmann S, Barber-Rotenberg JS, Yuan L, Abaan OD, Chou TH, Dakshanamurthy S, Brown ML, Uren A, Toretsky JA. Erkizan HV, et al. Among authors: kong y. Nat Med. 2009 Jul;15(7):750-6. doi: 10.1038/nm.1983. Epub 2009 Jul 5. Nat Med. 2009. PMID: 19584866 Free PMC article.

3

A boronic acid chalcone analog of combretastatin A-4 as a potent anti-proliferation agent.

Kong Y, Wang K, Edler MC, Hamel E, Mooberry SL, Paige MA, Brown ML. Kong Y, et al. Bioorg Med Chem. 2010 Jan 15;18(2):971-7. doi: 10.1016/j.bmc.2009.11.003. Epub 2009 Nov 10. Bioorg Med Chem. 2010. PMID: 20006519 Free PMC article.

4

YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion.

Rahim S, Beauchamp EM, Kong Y, Brown ML, Toretsky JA, Üren A. Rahim S, et al. Among authors: kong y. PLoS One. 2011 Apr 29;6(4):e19343. doi: 10.1371/journal.pone.0019343. PLoS One. 2011. PMID: 21559405 Free PMC article.

5

Histone deacetylase cytoplasmic trapping by a novel fluorescent HDAC inhibitor.

Kong Y, Jung M, Wang K, Grindrod S, Velena A, Lee SA, Dakshanamurthy S, Yang Y, Miessau M, Zheng C, Dritschilo A, Brown ML. Kong Y, et al. Mol Cancer Ther. 2011 Sep;10(9):1591-9. doi: 10.1158/1535-7163.MCT-10-0779. Epub 2011 Jun 22. Mol Cancer Ther. 2011. PMID: 21697394 Free PMC article.

6

Single enantiomer of YK-4-279 demonstrates specificity in targeting the oncogene EWS-FLI1.

Barber-Rotenberg JS, Selvanathan SP, Kong Y, Erkizan HV, Snyder TM, Hong SP, Kobs CL, South NL, Summer S, Monroe PJ, Chruszcz M, Dobrev V, Tosso PN, Scher LJ, Minor W, Brown ML, Metallo SJ, Üren A, Toretsky JA. Barber-Rotenberg JS, et al. Among authors: kong y. Oncotarget. 2012 Feb;3(2):172-82. doi: 10.18632/oncotarget.454. Oncotarget. 2012. PMID: 22383402 Free PMC article.

7

Trans-resveratrol boronic acid exhibits enhanced anti-proliferative activity on estrogen-dependent MCF-7 breast cancer cells.

Yenugonda VM, Kong Y, Deb TB, Yang Y, Riggins RB, Brown ML. Yenugonda VM, et al. Among authors: kong y. Cancer Biol Ther. 2012 Aug;13(10):925-34. doi: 10.4161/cbt.20845. Epub 2012 Aug 1. Cancer Biol Ther. 2012. PMID: 22785207 Free PMC article.

8

Preclinical studies of YK-4-272, an inhibitor of class II histone deacetylases by disruption of nucleocytoplasmic shuttling.

Kong HS, Tian S, Kong Y, Du G, Zhang L, Jung M, Dritschilo A, Brown ML. Kong HS, et al. Among authors: kong y. Pharm Res. 2012 Dec;29(12):3373-83. doi: 10.1007/s11095-012-0832-3. Epub 2012 Jul 27. Pharm Res. 2012. PMID: 22836184 Free PMC article.

9

Targeting mutant p53 by a SIRT1 activator YK-3-237 inhibits the proliferation of triple-negative breast cancer cells.

Yi YW, Kang HJ, Kim HJ, Kong Y, Brown ML, Bae I. Yi YW, et al. Among authors: kong y. Oncotarget. 2013 Jul;4(7):984-94. doi: 10.18632/oncotarget.1070. Oncotarget. 2013. PMID: 23846322 Free PMC article.

10

Novel carbazole inhibits phospho-STAT3 through induction of protein-tyrosine phosphatase PTPN6.

Hou S, Yi YW, Kang HJ, Zhang L, Kim HJ, Kong Y, Liu Y, Wang K, Kong HS, Grindrod S, Bae I, Brown ML. Hou S, et al. Among authors: kong y, kong hs. J Med Chem. 2014 Aug 14;57(15):6342-53. doi: 10.1021/jm4018042. Epub 2014 Aug 4. J Med Chem. 2014. PMID: 24978112 Free PMC article.

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