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The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase.
Gerken T, Girard CA, Tung YC, Webby CJ, Saudek V, Hewitson KS, Yeo GS, McDonough MA, Cunliffe S, McNeill LA, Galvanovskis J, Rorsman P, Robins P, Prieur X, Coll AP, Ma M, Jovanovic Z, Farooqi IS, Sedgwick B, Barroso I, Lindahl T, Ponting CP, Ashcroft FM, O'Rahilly S, Schofield CJ. Gerken T, et al. Among authors: yeo gs. Science. 2007 Nov 30;318(5855):1469-72. doi: 10.1126/science.1151710. Epub 2007 Nov 8. Science. 2007. PMID: 17991826 Free PMC article.
Where to go with FTO?
Larder R, Cheung MK, Tung YC, Yeo GS, Coll AP. Larder R, et al. Among authors: yeo gs. Trends Endocrinol Metab. 2011 Feb;22(2):53-9. doi: 10.1016/j.tem.2010.11.001. Epub 2010 Dec 4. Trends Endocrinol Metab. 2011. PMID: 21131211 Review.
From GWAS to biology: lessons from FTO.
Tung YC, Yeo GS. Tung YC, et al. Among authors: yeo gs. Ann N Y Acad Sci. 2011 Mar;1220:162-71. doi: 10.1111/j.1749-6632.2010.05903.x. Ann N Y Acad Sci. 2011. PMID: 21388413 Review.
301 results