Wynn R - Search Results

1

Heparin cofactor II-thrombin complex and dermatan sulphate:chondroitin sulphate ratio are biomarkers of short- and long-term treatment effects in mucopolysaccharide diseases.

Langford-Smith KJ, Mercer J, Petty J, Tylee K, Church H, Roberts J, Moss G, Jones S, Wynn R, Wraith JE, Bigger BW. Langford-Smith KJ, et al. Among authors: wynn r. J Inherit Metab Dis. 2011 Apr;34(2):499-508. doi: 10.1007/s10545-010-9254-8. Epub 2010 Dec 18. J Inherit Metab Dis. 2011. PMID: 21170681 Free PMC article.

2

Donor bone marrow from a sibling with inborn error of metabolism for treatment of acute leukaemia - clinical and biochemical consequences in the non-affected recipient.

Meyer S, Thornley M, Wynn RF, Brennan BM, Carr T, Wraith JE, Will AM. Meyer S, et al. Among authors: wynn rf. Bone Marrow Transplant. 2000 Apr;25(8):909-11. doi: 10.1038/sj.bmt.1702333. Bone Marrow Transplant. 2000. PMID: 10808215

3

Retrovirally mediated correction of bone marrow-derived mesenchymal stem cells from patients with mucopolysaccharidosis type I.

Baxter MA, Wynn RF, Deakin JA, Bellantuono I, Edington KG, Cooper A, Besley GT, Church HJ, Wraith JE, Carr TF, Fairbairn LJ. Baxter MA, et al. Blood. 2002 Mar 1;99(5):1857-9. doi: 10.1182/blood.v99.5.1857. Blood. 2002. PMID: 11861306 Free article.

4

A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow.

Wynn RF, Hart CA, Corradi-Perini C, O'Neill L, Evans CA, Wraith JE, Fairbairn LJ, Bellantuono I. Wynn RF, et al. Blood. 2004 Nov 1;104(9):2643-5. doi: 10.1182/blood-2004-02-0526. Epub 2004 Jul 13. Blood. 2004. PMID: 15251986 Free article.

5

Study of telomere length reveals rapid aging of human marrow stromal cells following in vitro expansion.

Baxter MA, Wynn RF, Jowitt SN, Wraith JE, Fairbairn LJ, Bellantuono I. Baxter MA, et al. Stem Cells. 2004;22(5):675-82. doi: 10.1634/stemcells.22-5-675. Stem Cells. 2004. PMID: 15342932

6

Marrow stromal cells from patients affected by MPS I differentially support haematopoietic progenitor cell development.

Baxter MA, Wynn RF, Schyma L, Holmes DK, Wraith JE, Fairbairn LJ, Bellantuono I. Baxter MA, et al. Among authors: wynn rf. J Inherit Metab Dis. 2005;28(6):1045-53. doi: 10.1007/s10545-005-0136-4. J Inherit Metab Dis. 2005. PMID: 16435198

7

Haematopoietic cell transplantation (HCT) in combination with enzyme replacement therapy (ERT) in patients with Hurler syndrome.

Cox-Brinkman J, Boelens JJ, Wraith JE, O'meara A, Veys P, Wijburg FA, Wulffraat N, Wynn RF. Cox-Brinkman J, et al. Among authors: wynn rf. Bone Marrow Transplant. 2006 Jul;38(1):17-21. doi: 10.1038/sj.bmt.1705401. Epub 2006 May 22. Bone Marrow Transplant. 2006. PMID: 16715104 Clinical Trial.

8

Biochemical monitoring after haemopoietic stem cell transplant for Hurler syndrome (MPSIH): implications for functional outcome after transplant in metabolic disease.

Church H, Tylee K, Cooper A, Thornley M, Mercer J, Wraith E, Carr T, O'Meara A, Wynn RF. Church H, et al. Among authors: wynn rf. Bone Marrow Transplant. 2007 Feb;39(4):207-10. doi: 10.1038/sj.bmt.1705569. Epub 2007 Jan 15. Bone Marrow Transplant. 2007. PMID: 17220904

9

Use of enzyme replacement therapy (Laronidase) before hematopoietic stem cell transplantation for mucopolysaccharidosis I: experience in 18 patients.

Wynn RF, Mercer J, Page J, Carr TF, Jones S, Wraith JE. Wynn RF, et al. J Pediatr. 2009 Jan;154(1):135-9. doi: 10.1016/j.jpeds.2008.07.004. J Pediatr. 2009. PMID: 19187736

10

Improved metabolic correction in patients with lysosomal storage disease treated with hematopoietic stem cell transplant compared with enzyme replacement therapy.

Wynn RF, Wraith JE, Mercer J, O'Meara A, Tylee K, Thornley M, Church HJ, Bigger BW. Wynn RF, et al. J Pediatr. 2009 Apr;154(4):609-11. doi: 10.1016/j.jpeds.2008.11.005. J Pediatr. 2009. PMID: 19324223 Clinical Trial.

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