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Page 1
Integrity of mTORC2 is dependent on the rictor Gly-934 site.
Aimbetov R, Chen CH, Bulgakova O, Abetov D, Bissenbaev AK, Bersimbaev RI, Sarbassov DD. Aimbetov R, et al. Oncogene. 2012 Apr 19;31(16):2115-20. doi: 10.1038/onc.2011.404. Epub 2011 Sep 12. Oncogene. 2012. PMID: 21909137 Free PMC article.
Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1.
Jin G, Lee SW, Zhang X, Cai Z, Gao Y, Chou PC, Rezaeian AH, Han F, Wang CY, Yao JC, Gong Z, Chan CH, Huang CY, Tsai FJ, Tsai CH, Tu SH, Wu CH, Sarbassov dos D, Ho YS, Lin HK. Jin G, et al. Among authors: sarbassov dos d. Mol Cell. 2015 Jun 18;58(6):989-1000. doi: 10.1016/j.molcel.2015.05.010. Epub 2015 Jun 4. Mol Cell. 2015. PMID: 26051179 Free PMC article.
The nuclear import of ribosomal proteins is regulated by mTOR.
Kazyken D, Kaz Y, Kiyan V, Zhylkibayev AA, Chen CH, Agarwal NK, Sarbassov dos D. Kazyken D, et al. Among authors: sarbassov dos d. Oncotarget. 2014 Oct 30;5(20):9577-93. doi: 10.18632/oncotarget.2473. Oncotarget. 2014. PMID: 25294810 Free PMC article.
Endoplasmic reticulum is a main localization site of mTORC2.
Boulbés DR, Shaiken T, Sarbassov dos D. Boulbés DR, et al. Among authors: sarbassov dos d. Biochem Biophys Res Commun. 2011 Sep 16;413(1):46-52. doi: 10.1016/j.bbrc.2011.08.034. Epub 2011 Aug 16. Biochem Biophys Res Commun. 2011. PMID: 21867682 Free PMC article.
Rictor regulates cell migration by suppressing RhoGDI2.
Agarwal NK, Chen CH, Cho H, Boulbès DR, Spooner E, Sarbassov DD. Agarwal NK, et al. Oncogene. 2013 May 16;32(20):2521-6. doi: 10.1038/onc.2012.287. Epub 2012 Jul 9. Oncogene. 2013. PMID: 22777355 Free PMC article.
Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.
Zeng Z, Sarbassov dos D, Samudio IJ, Yee KW, Munsell MF, Ellen Jackson C, Giles FJ, Sabatini DM, Andreeff M, Konopleva M. Zeng Z, et al. Among authors: sarbassov dos d. Blood. 2007 Apr 15;109(8):3509-12. doi: 10.1182/blood-2006-06-030833. Epub 2006 Dec 19. Blood. 2007. PMID: 17179228 Free PMC article.
33 results