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Small molecule inhibitors of Staphylococcus aureus RnpA alter cellular mRNA turnover, exhibit antimicrobial activity, and attenuate pathogenesis.
Olson PD, Kuechenmeister LJ, Anderson KL, Daily S, Beenken KE, Roux CM, Reniere ML, Lewis TL, Weiss WJ, Pulse M, Nguyen P, Simecka JW, Morrison JM, Sayood K, Asojo OA, Smeltzer MS, Skaar EP, Dunman PM. Olson PD, et al. Among authors: anderson kl. PLoS Pathog. 2011 Feb 10;7(2):e1001287. doi: 10.1371/journal.ppat.1001287. PLoS Pathog. 2011. PMID: 21347352 Free PMC article.
The staphylococcal accessory regulator, SarA, is an RNA-binding protein that modulates the mRNA turnover properties of late-exponential and stationary phase Staphylococcus aureus cells.
Morrison JM, Anderson KL, Beenken KE, Smeltzer MS, Dunman PM. Morrison JM, et al. Among authors: anderson kl. Front Cell Infect Microbiol. 2012 Mar 8;2:26. doi: 10.3389/fcimb.2012.00026. eCollection 2012. Front Cell Infect Microbiol. 2012. PMID: 22919618 Free PMC article.
461 results