Yakel JL - Search Results

1

A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors.

Brams M, Pandya A, Kuzmin D, van Elk R, Krijnen L, Yakel JL, Tsetlin V, Smit AB, Ulens C. Brams M, et al. Among authors: yakel jl. PLoS Biol. 2011 Mar;9(3):e1001034. doi: 10.1371/journal.pbio.1001034. Epub 2011 Mar 29. PLoS Biol. 2011. PMID: 21468359 Free PMC article.

2

Crystal structures of a cysteine-modified mutant in loop D of acetylcholine-binding protein.

Brams M, Gay EA, Sáez JC, Guskov A, van Elk R, van der Schors RC, Peigneur S, Tytgat J, Strelkov SV, Smit AB, Yakel JL, Ulens C. Brams M, et al. Among authors: yakel jl. J Biol Chem. 2011 Feb 11;286(6):4420-8. doi: 10.1074/jbc.M110.188730. Epub 2010 Nov 29. J Biol Chem. 2011. PMID: 21115477 Free PMC article.

3

Molecular actions of smoking cessation drugs at α4β2 nicotinic receptors defined in crystal structures of a homologous binding protein.

Billen B, Spurny R, Brams M, van Elk R, Valera-Kummer S, Yakel JL, Voets T, Bertrand D, Smit AB, Ulens C. Billen B, et al. Among authors: yakel jl. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9173-8. doi: 10.1073/pnas.1116397109. Epub 2012 May 22. Proc Natl Acad Sci U S A. 2012. PMID: 22619328 Free PMC article.

4

Allosteric modulators of the α4β2 subtype of neuronal nicotinic acetylcholine receptors.

Pandya A, Yakel JL. Pandya A, et al. Among authors: yakel jl. Biochem Pharmacol. 2011 Oct 15;82(8):952-8. doi: 10.1016/j.bcp.2011.04.020. Epub 2011 May 7. Biochem Pharmacol. 2011. PMID: 21596025 Free PMC article. Review.

5

Allosteric modulator Desformylflustrabromine relieves the inhibition of α2β2 and α4β2 nicotinic acetylcholine receptors by β-amyloid(1-42) peptide.

Pandya A, Yakel JL. Pandya A, et al. Among authors: yakel jl. J Mol Neurosci. 2011 Sep;45(1):42-7. doi: 10.1007/s12031-011-9509-3. Epub 2011 Mar 22. J Mol Neurosci. 2011. PMID: 21424792 Free PMC article.

6

Activation of the α7 nicotinic ACh receptor induces anxiogenic effects in rats which is blocked by a 5-HT₁a receptor antagonist.

Pandya AA, Yakel JL. Pandya AA, et al. Among authors: yakel jl. Neuropharmacology. 2013 Jul;70:35-42. doi: 10.1016/j.neuropharm.2013.01.004. Epub 2013 Jan 12. Neuropharmacology. 2013. PMID: 23321689 Free PMC article.

7

Levamisole: A Positive Allosteric Modulator for the α3β4 Nicotinic Acetylcholine Receptors Prevents Weight Gain in the CD-1 Mice on a High Fat Diet.

Lewis JA, Yakel JL, Pandya AA. Lewis JA, et al. Among authors: yakel jl. Curr Pharm Des. 2017;23(12):1869-1872. doi: 10.2174/1381612822666161201145648. Curr Pharm Des. 2017. PMID: 27908269 Free PMC article.

8

Effects of neuronal nicotinic acetylcholine receptor allosteric modulators in animal behavior studies.

Pandya AA, Yakel JL. Pandya AA, et al. Among authors: yakel jl. Biochem Pharmacol. 2013 Oct 15;86(8):1054-62. doi: 10.1016/j.bcp.2013.05.018. Epub 2013 May 31. Biochem Pharmacol. 2013. PMID: 23732296 Free PMC article. Review.

9

Nicotinic ACh receptors as therapeutic targets in CNS disorders.

Dineley KT, Pandya AA, Yakel JL. Dineley KT, et al. Among authors: yakel jl. Trends Pharmacol Sci. 2015 Feb;36(2):96-108. doi: 10.1016/j.tips.2014.12.002. Epub 2015 Jan 29. Trends Pharmacol Sci. 2015. PMID: 25639674 Free PMC article. Review.

10

Absolute Configuration and Pharmacology of the Poison Frog Alkaloid Phantasmidine.

Fitch RW, Snider BB, Zhou Q, Foxman BM, Pandya AA, Yakel JL, Olson TT, Al-Muhtasib N, Xiao Y, Welch KD, Panter KE. Fitch RW, et al. Among authors: yakel jl. J Nat Prod. 2018 Apr 27;81(4):1029-1035. doi: 10.1021/acs.jnatprod.8b00062. Epub 2018 Apr 19. J Nat Prod. 2018. PMID: 29671588 Free PMC article.

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