Gunn RN - Search Results

1

Pharmacological differentiation of opioid receptor antagonists by molecular and functional imaging of target occupancy and food reward-related brain activation in humans.

Rabiner EA, Beaver J, Makwana A, Searle G, Long C, Nathan PJ, Newbould RD, Howard J, Miller SR, Bush MA, Hill S, Reiley R, Passchier J, Gunn RN, Matthews PM, Bullmore ET. Rabiner EA, et al. Among authors: gunn rn. Mol Psychiatry. 2011 Aug;16(8):826-35, 785. doi: 10.1038/mp.2011.29. Epub 2011 Apr 19. Mol Psychiatry. 2011. PMID: 21502953 Free PMC article. Clinical Trial.

2

Tracer kinetic modeling of the 5-HT1A receptor ligand [carbonyl-11C]WAY-100635 for PET.

Gunn RN, Sargent PA, Bench CJ, Rabiner EA, Osman S, Pike VW, Hume SP, Grasby PM, Lammertsma AA. Gunn RN, et al. Neuroimage. 1998 Nov;8(4):426-40. doi: 10.1006/nimg.1998.0379. Neuroimage. 1998. PMID: 9811559 Clinical Trial.

3

Brain serotonin1A receptor binding measured by positron emission tomography with [11C]WAY-100635: effects of depression and antidepressant treatment.

Sargent PA, Kjaer KH, Bench CJ, Rabiner EA, Messa C, Meyer J, Gunn RN, Grasby PM, Cowen PJ. Sargent PA, et al. Among authors: gunn rn. Arch Gen Psychiatry. 2000 Feb;57(2):174-80. doi: 10.1001/archpsyc.57.2.174. Arch Gen Psychiatry. 2000. PMID: 10665620

4

beta-blocker binding to human 5-HT(1A) receptors in vivo and in vitro: implications for antidepressant therapy.

Rabiner EA, Gunn RN, Castro ME, Sargent PA, Cowen PJ, Koepp MJ, Meyer JH, Bench CJ, Harrison PJ, Pazos A, Sharp T, Grasby PM. Rabiner EA, et al. Among authors: gunn rn. Neuropsychopharmacology. 2000 Sep;23(3):285-93. doi: 10.1016/S0893-133X(00)00109-3. Neuropsychopharmacology. 2000. PMID: 10942852 Clinical Trial.

5

Drug action at the 5-HT(1A) receptor in vivo: autoreceptor and postsynaptic receptor occupancy examined with PET and [carbonyl-(11)C]WAY-100635.

Rabiner EA, Gunn RN, Wilkins MR, Sargent PA, Mocaer E, Sedman E, Cowen PJ, Grasby PM. Rabiner EA, et al. Among authors: gunn rn. Nucl Med Biol. 2000 Jul;27(5):509-13. doi: 10.1016/s0969-8051(00)00120-7. Nucl Med Biol. 2000. PMID: 10962259

6

Pindolol augmentation of selective serotonin reuptake inhibitors: PET evidence that the dose used in clinical trials is too low.

Rabiner EA, Bhagwagar Z, Gunn RN, Sargent PA, Bench CJ, Cowen PJ, Grasby PM. Rabiner EA, et al. Among authors: gunn rn. Am J Psychiatry. 2001 Dec;158(12):2080-2. doi: 10.1176/appi.ajp.158.12.2080. Am J Psychiatry. 2001. PMID: 11729033

7

A database of [(11)C]WAY-100635 binding to 5-HT(1A) receptors in normal male volunteers: normative data and relationship to methodological, demographic, physiological, and behavioral variables.

Rabiner EA, Messa C, Sargent PA, Husted-Kjaer K, Montgomery A, Lawrence AD, Bench CJ, Gunn RN, Cowen P, Grasby PM. Rabiner EA, et al. Among authors: gunn rn. Neuroimage. 2002 Mar;15(3):620-32. doi: 10.1006/nimg.2001.0984. Neuroimage. 2002. PMID: 11848705

8

5-Hydroxytryptamine1A receptor occupancy by novel full antagonist 2-[4-[4-(7-chloro-2,3-dihydro-1,4-benzdioxyn-5-yl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3-(2H)-one-1,1-dioxide: a[11C][O-methyl-3H]-N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide trihydrochloride (WAY-100635) positron emission tomography study in humans.

Rabiner EA, Wilkins MR, Turkheimer F, Gunn RN, Udo de Haes J, de Vries M, Grasby PM. Rabiner EA, et al. Among authors: gunn rn. J Pharmacol Exp Ther. 2002 Jun;301(3):1144-50. doi: 10.1124/jpet.301.3.1144. J Pharmacol Exp Ther. 2002. PMID: 12023549

9

Evaluation of EMD 128 130 occupancy of the 5-HT1A and the D2 receptor: a human PET study with [11C]WAY-100635 and [11C]raclopride.

Rabiner EA, Gunn RN, Wilkins MR, Sedman E, Grasby PM. Rabiner EA, et al. Among authors: gunn rn. J Psychopharmacol. 2002 Sep;16(3):195-9. doi: 10.1177/026988110201600301. J Psychopharmacol. 2002. PMID: 12236624

10

Preferential 5-HT1A autoreceptor occupancy by pindolol is attenuated in depressed patients: effect of treatment or an endophenotype of depression?

Rabiner EA, Bhagwagar Z, Gunn RN, Cowen PJ, Grasby PM. Rabiner EA, et al. Among authors: gunn rn. Neuropsychopharmacology. 2004 Sep;29(9):1688-98. doi: 10.1038/sj.npp.1300472. Neuropsychopharmacology. 2004. PMID: 15127080 Clinical Trial.

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