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Disruption of hexokinase II-mitochondrial binding blocks ischemic preconditioning and causes rapid cardiac necrosis.
Smeele KM, Southworth R, Wu R, Xie C, Nederlof R, Warley A, Nelson JK, van Horssen P, van den Wijngaard JP, Heikkinen S, Laakso M, Koeman A, Siebes M, Eerbeek O, Akar FG, Ardehali H, Hollmann MW, Zuurbier CJ. Smeele KM, et al. Among authors: nelson jk. Circ Res. 2011 May 13;108(10):1165-9. doi: 10.1161/CIRCRESAHA.111.244962. Epub 2011 Apr 28. Circ Res. 2011. PMID: 21527739
Reduced hexokinase II impairs muscle function 2 wk after ischemia-reperfusion through increased cell necrosis and fibrosis.
Smeele KM, Eerbeek O, Schaart G, Koeman A, Bezemer R, Nelson JK, Ince C, Nederlof R, Boek M, Laakso M, de Haan A, Drost MR, Hollmann MW, Zuurbier CJ. Smeele KM, et al. Among authors: nelson jk. J Appl Physiol (1985). 2012 Aug 15;113(4):608-18. doi: 10.1152/japplphysiol.01494.2011. Epub 2012 Jun 21. J Appl Physiol (1985). 2012. PMID: 22723631 Free article.
A Specific Activity-Based Probe to Monitor Family GH59 Galactosylceramidase, the Enzyme Deficient in Krabbe Disease.
Marques AR, Willems LI, Herrera Moro D, Florea BI, Scheij S, Ottenhoff R, van Roomen CP, Verhoek M, Nelson JK, Kallemeijn WW, Biela-Banas A, Martin OR, Cachón-González MB, Kim NN, Cox TM, Boot RG, Overkleeft HS, Aerts JM. Marques AR, et al. Among authors: nelson jk. Chembiochem. 2017 Feb 16;18(4):402-412. doi: 10.1002/cbic.201600561. Epub 2017 Jan 31. Chembiochem. 2017. PMID: 28000364 Free article.
190 results