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Disruption of hexokinase II-mitochondrial binding blocks ischemic preconditioning and causes rapid cardiac necrosis.
Smeele KM, Southworth R, Wu R, Xie C, Nederlof R, Warley A, Nelson JK, van Horssen P, van den Wijngaard JP, Heikkinen S, Laakso M, Koeman A, Siebes M, Eerbeek O, Akar FG, Ardehali H, Hollmann MW, Zuurbier CJ. Smeele KM, et al. Among authors: wu r. Circ Res. 2011 May 13;108(10):1165-9. doi: 10.1161/CIRCRESAHA.111.244962. Epub 2011 Apr 28. Circ Res. 2011. PMID: 21527739
Regulation and cytoprotective role of hexokinase III.
Wyatt E, Wu R, Rabeh W, Park HW, Ghanefar M, Ardehali H. Wyatt E, et al. Among authors: wu r. PLoS One. 2010 Nov 3;5(11):e13823. doi: 10.1371/journal.pone.0013823. PLoS One. 2010. PMID: 21072205 Free PMC article.
ATP-binding cassette B10 regulates early steps of heme synthesis.
Bayeva M, Khechaduri A, Wu R, Burke MA, Wasserstrom JA, Singh N, Liesa M, Shirihai OS, Langer NB, Paw BH, Ardehali H. Bayeva M, et al. Among authors: wu r. Circ Res. 2013 Jul 19;113(3):279-87. doi: 10.1161/CIRCRESAHA.113.301552. Epub 2013 May 29. Circ Res. 2013. PMID: 23720443 Free PMC article.
When less is more: novel mechanisms of iron conservation.
Bayeva M, Chang HC, Wu R, Ardehali H. Bayeva M, et al. Among authors: wu r. Trends Endocrinol Metab. 2013 Nov;24(11):569-77. doi: 10.1016/j.tem.2013.07.003. Epub 2013 Aug 12. Trends Endocrinol Metab. 2013. PMID: 23948590 Free PMC article. Review.
Increased Heme Levels in the Heart Lead to Exacerbated Ischemic Injury.
Sawicki KT, Shang M, Wu R, Chang HC, Khechaduri A, Sato T, Kamide C, Liu T, Naga Prasad SV, Ardehali H. Sawicki KT, et al. Among authors: wu r. J Am Heart Assoc. 2015 Jul 31;4(8):e002272. doi: 10.1161/JAHA.115.002272. J Am Heart Assoc. 2015. PMID: 26231844 Free PMC article.
Reduction in mitochondrial iron alleviates cardiac damage during injury.
Chang HC, Wu R, Shang M, Sato T, Chen C, Shapiro JS, Liu T, Thakur A, Sawicki KT, Prasad SV, Ardehali H. Chang HC, et al. Among authors: wu r. EMBO Mol Med. 2016 Mar 1;8(3):247-67. doi: 10.15252/emmm.201505748. EMBO Mol Med. 2016. PMID: 26896449 Free PMC article.
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