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Page 1
Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: part 1.
Matasi JJ, Brumfield S, Tulshian D, Czarnecki M, Greenlee W, Garlisi CG, Qiu H, Devito K, Chen SC, Sun Y, Bertorelli R, Geiss W, Le VD, Martin GS, Vellekoop SA, Haber J, Allard ML. Matasi JJ, et al. Among authors: geiss w. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3805-8. doi: 10.1016/j.bmcl.2011.04.034. Epub 2011 Apr 24. Bioorg Med Chem Lett. 2011. PMID: 21570840
Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: part 2.
Brumfield S, Matasi JJ, Tulshian D, Czarniecki M, Greenlee W, Garlisi C, Qiu H, Devito K, Chen SC, Sun Y, Bertorelli R, Ansell J, Geiss W, Le VD, Martin GS, Vellekoop SA, Haber J, Allard ML. Brumfield S, et al. Among authors: geiss w. Bioorg Med Chem Lett. 2011 Dec 15;21(24):7287-90. doi: 10.1016/j.bmcl.2011.10.037. Epub 2011 Oct 21. Bioorg Med Chem Lett. 2011. PMID: 22078214
Design, synthesis, and structure-activity relationships of novel 2-substituted pyrazinoylguanidine epithelial sodium channel blockers: drugs for cystic fibrosis and chronic bronchitis.
Hirsh AJ, Molino BF, Zhang J, Astakhova N, Geiss WB, Sargent BJ, Swenson BD, Usyatinsky A, Wyle MJ, Boucher RC, Smith RT, Zamurs A, Johnson MR. Hirsh AJ, et al. Among authors: geiss wb. J Med Chem. 2006 Jul 13;49(14):4098-115. doi: 10.1021/jm051134w. J Med Chem. 2006. PMID: 16821771
Synthesis and pharmacological evaluation of novel gamma-aminobutyric acid type B (GABAB) receptor agonists as gastroesophageal reflux inhibitors.
Alstermark C, Amin K, Dinn SR, Elebring T, Fjellström O, Fitzpatrick K, Geiss WB, Gottfries J, Guzzo PR, Harding JP, Holmén A, Kothare M, Lehmann A, Mattsson JP, Nilsson K, Sundén G, Swanson M, von Unge S, Woo AM, Wyle MJ, Zheng X. Alstermark C, et al. Among authors: geiss wb. J Med Chem. 2008 Jul 24;51(14):4315-20. doi: 10.1021/jm701425k. Epub 2008 Jun 25. J Med Chem. 2008. PMID: 18578471
Effects of (2R)-(3-amino-2-fluoropropyl)sulphinic acid (AFPSiA) on transient lower oesophageal sphincter relaxation in dogs and mechanism of hypothermic effects in mice.
Lehmann A, Holmberg AA, Bhatt U, Bremner-Danielsen M, Brändén L, Elg S, Elebring T, Fitzpatrick K, Geiss WB, Guzzo P, Jensen J, Jerndal G, Mattsson JP, Nilsson K, Olsson BM. Lehmann A, et al. Among authors: geiss wb. Br J Pharmacol. 2005 Sep;146(1):89-97. doi: 10.1038/sj.bjp.0706299. Br J Pharmacol. 2005. PMID: 15980875 Free PMC article.