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Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: part 1.
Matasi JJ, Brumfield S, Tulshian D, Czarnecki M, Greenlee W, Garlisi CG, Qiu H, Devito K, Chen SC, Sun Y, Bertorelli R, Geiss W, Le VD, Martin GS, Vellekoop SA, Haber J, Allard ML. Matasi JJ, et al. Among authors: le vd. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3805-8. doi: 10.1016/j.bmcl.2011.04.034. Epub 2011 Apr 24. Bioorg Med Chem Lett. 2011. PMID: 21570840
Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: part 2.
Brumfield S, Matasi JJ, Tulshian D, Czarniecki M, Greenlee W, Garlisi C, Qiu H, Devito K, Chen SC, Sun Y, Bertorelli R, Ansell J, Geiss W, Le VD, Martin GS, Vellekoop SA, Haber J, Allard ML. Brumfield S, et al. Among authors: le vd. Bioorg Med Chem Lett. 2011 Dec 15;21(24):7287-90. doi: 10.1016/j.bmcl.2011.10.037. Epub 2011 Oct 21. Bioorg Med Chem Lett. 2011. PMID: 22078214
3-(Arylsulfonyl)-1-(azacyclyl)-1H-indoles are 5-HT(6) receptor modulators.
Bernotas RC, Antane S, Shenoy R, Le VD, Chen P, Harrison BL, Robichaud AJ, Zhang GM, Smith D, Schechter LE. Bernotas RC, et al. Among authors: le vd. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1657-60. doi: 10.1016/j.bmcl.2010.01.073. Epub 2010 Jan 21. Bioorg Med Chem Lett. 2010. PMID: 20138763
77 results