Simons SS Jr - Search Results

1

An Approach to Greater Specificity for Glucocorticoids.

Chow CC, Simons SS Jr. Chow CC, et al. Among authors: simons ss jr. Front Endocrinol (Lausanne). 2018 Mar 13;9:76. doi: 10.3389/fendo.2018.00076. eCollection 2018. Front Endocrinol (Lausanne). 2018. PMID: 29593646 Free PMC article. Review.

2

Kinetically Defined Mechanisms and Positions of Action of Two New Modulators of Glucocorticoid Receptor-regulated Gene Induction.

Pradhan MA, Blackford JA Jr, Devaiah BN, Thompson PS, Chow CC, Singer DS, Simons SS Jr. Pradhan MA, et al. Among authors: simons ss jr. J Biol Chem. 2016 Jan 1;291(1):342-54. doi: 10.1074/jbc.M115.683722. Epub 2015 Oct 26. J Biol Chem. 2016. PMID: 26504077 Free PMC article.

3

Theory of partial agonist activity of steroid hormones.

Chow CC, Ong KM, Kagan B, Simons SS Jr. Chow CC, et al. Among authors: simons ss jr. AIMS Mol Sci. 2015;2(2):101-123. doi: 10.3934/molsci.2015.2.101#sthash.jxRCteJz.dpuf. AIMS Mol Sci. 2015. PMID: 25984562 Free PMC article.

4

Kinetically-defined component actions in gene repression.

Chow CC, Finn KK, Storchan GB, Lu X, Sheng X, Simons SS Jr. Chow CC, et al. Among authors: simons ss jr. PLoS Comput Biol. 2015 Mar 27;11(3):e1004122. doi: 10.1371/journal.pcbi.1004122. eCollection 2015 Mar. PLoS Comput Biol. 2015. PMID: 25816223 Free PMC article.

5

The use of mode of action information in risk assessment: quantitative key events/dose-response framework for modeling the dose-response for key events.

Simon TW, Simons SS Jr, Preston RJ, Boobis AR, Cohen SM, Doerrer NG, Fenner-Crisp PA, McMullin TS, McQueen CA, Rowlands JC; RISK21 Dose-Response Subteam. Simon TW, et al. Among authors: simons ss jr. Crit Rev Toxicol. 2014 Aug;44 Suppl 3:17-43. doi: 10.3109/10408444.2014.931925. Crit Rev Toxicol. 2014. PMID: 25070415 Review.

6

Research resource: modulators of glucocorticoid receptor activity identified by a new high-throughput screening assay.

Blackford JA Jr, Brimacombe KR, Dougherty EJ, Pradhan M, Shen M, Li Z, Auld DS, Chow CC, Austin CP, Simons SS Jr. Blackford JA Jr, et al. Among authors: simons ss jr. Mol Endocrinol. 2014 Jul;28(7):1194-206. doi: 10.1210/me.2014-1069. Epub 2014 May 21. Mol Endocrinol. 2014. PMID: 24850414 Free PMC article.

7

A kinase-independent activity of Cdk9 modulates glucocorticoid receptor-mediated gene induction.

Zhu R, Lu X, Pradhan M, Armstrong SP, Storchan GB, Chow CC, Simons SS Jr. Zhu R, et al. Among authors: simons ss jr. Biochemistry. 2014 Mar 25;53(11):1753-67. doi: 10.1021/bi5000178. Epub 2014 Mar 11. Biochemistry. 2014. PMID: 24559102 Free PMC article.

8

Minireview: dynamic structures of nuclear hormone receptors: new promises and challenges.

Simons SS Jr, Edwards DP, Kumar R. Simons SS Jr, et al. Mol Endocrinol. 2014 Feb;28(2):173-82. doi: 10.1210/me.2013-1334. Epub 2013 Nov 27. Mol Endocrinol. 2014. PMID: 24284822 Free PMC article. Review.

9

A conserved protein motif is required for full modulatory activity of negative elongation factor subunits NELF-A and NELF-B in modifying glucocorticoid receptor-regulated gene induction properties.

Luo M, Lu X, Zhu R, Zhang Z, Chow CC, Li R, Simons SS Jr. Luo M, et al. Among authors: simons ss jr. J Biol Chem. 2013 Nov 22;288(47):34055-34072. doi: 10.1074/jbc.M113.512426. Epub 2013 Oct 6. J Biol Chem. 2013. PMID: 24097989 Free PMC article.

10

Variable steroid receptor responses: Intrinsically disordered AF1 is the key.

Simons SS Jr, Kumar R. Simons SS Jr, et al. Mol Cell Endocrinol. 2013 Aug 25;376(1-2):81-4. doi: 10.1016/j.mce.2013.06.007. Epub 2013 Jun 17. Mol Cell Endocrinol. 2013. PMID: 23792173 Free PMC article. Review.

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