Tian Z - Search Results

1

In vitro and in vivo selective antitumor activity of a novel orally bioavailable proteasome inhibitor MLN9708 against multiple myeloma cells.

Chauhan D, Tian Z, Zhou B, Kuhn D, Orlowski R, Raje N, Richardson P, Anderson KC. Chauhan D, et al. Among authors: tian z. Clin Cancer Res. 2011 Aug 15;17(16):5311-21. doi: 10.1158/1078-0432.CCR-11-0476. Epub 2011 Jun 30. Clin Cancer Res. 2011. PMID: 21724551 Free PMC article.

2

A novel TLR-9 agonist C792 inhibits plasmacytoid dendritic cell-induced myeloma cell growth and enhance cytotoxicity of bortezomib.

Ray A, Tian Z, Das DS, Coffman RL, Richardson P, Chauhan D, Anderson KC. Ray A, et al. Among authors: tian z. Leukemia. 2014 Aug;28(8):1716-24. doi: 10.1038/leu.2014.46. Epub 2014 Jan 30. Leukemia. 2014. PMID: 24476765 Free PMC article.

3

A novel hypoxia-selective epigenetic agent RRx-001 triggers apoptosis and overcomes drug resistance in multiple myeloma cells.

Das DS, Ray A, Das A, Song Y, Tian Z, Oronsky B, Richardson P, Scicinski J, Chauhan D, Anderson KC. Das DS, et al. Among authors: tian z. Leukemia. 2016 Nov;30(11):2187-2197. doi: 10.1038/leu.2016.96. Epub 2016 Apr 27. Leukemia. 2016. PMID: 27118403 Free PMC article.

4

A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance.

Chauhan D, Tian Z, Nicholson B, Kumar KG, Zhou B, Carrasco R, McDermott JL, Leach CA, Fulcinniti M, Kodrasov MP, Weinstock J, Kingsbury WD, Hideshima T, Shah PK, Minvielle S, Altun M, Kessler BM, Orlowski R, Richardson P, Munshi N, Anderson KC. Chauhan D, et al. Among authors: tian z. Cancer Cell. 2012 Sep 11;22(3):345-58. doi: 10.1016/j.ccr.2012.08.007. Cancer Cell. 2012. PMID: 22975377 Free PMC article.

5

Investigational agent MLN9708/2238 targets tumor-suppressor miR33b in MM cells.

Tian Z, Zhao JJ, Tai YT, Amin SB, Hu Y, Berger AJ, Richardson P, Chauhan D, Anderson KC. Tian Z, et al. Blood. 2012 Nov 8;120(19):3958-67. doi: 10.1182/blood-2012-01-401794. Epub 2012 Sep 14. Blood. 2012. PMID: 22983447 Free PMC article.

6

A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance.

Tian Z, D'Arcy P, Wang X, Ray A, Tai YT, Hu Y, Carrasco RD, Richardson P, Linder S, Chauhan D, Anderson KC. Tian Z, et al. Blood. 2014 Jan 30;123(5):706-16. doi: 10.1182/blood-2013-05-500033. Epub 2013 Dec 6. Blood. 2014. PMID: 24319254 Free PMC article.

7

Preclinical activity of the oral proteasome inhibitor MLN9708 in Myeloma bone disease.

Garcia-Gomez A, Quwaider D, Canavese M, Ocio EM, Tian Z, Blanco JF, Berger AJ, Ortiz-de-Solorzano C, Hernández-Iglesias T, Martens AC, Groen RW, Mateo-Urdiales J, Fraile S, Galarraga M, Chauhan D, San Miguel JF, Raje N, Garayoa M. Garcia-Gomez A, et al. Among authors: tian z. Clin Cancer Res. 2014 Mar 15;20(6):1542-54. doi: 10.1158/1078-0432.CCR-13-1657. Epub 2014 Jan 31. Clin Cancer Res. 2014. PMID: 24486586

8

HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells.

Song W, Tai YT, Tian Z, Hideshima T, Chauhan D, Nanjappa P, Exley MA, Anderson KC, Munshi NC. Song W, et al. Among authors: tian z. Leukemia. 2011 Jan;25(1):161-8. doi: 10.1038/leu.2010.244. Epub 2010 Nov 19. Leukemia. 2011. PMID: 21102427 Free PMC article.

9

A novel rapid-onset high-penetrance plasmacytoma mouse model driven by deregulation of cMYC cooperating with KRAS12V in BALB/c mice.

Hu Y, Zheng M, Gali R, Tian Z, Topal Görgün G, Munshi NC, Mitsiades CS, Anderson KC. Hu Y, et al. Among authors: tian z. Blood Cancer J. 2013 Nov 1;3(11):e156. doi: 10.1038/bcj.2013.53. Blood Cancer J. 2013. PMID: 24185503 Free PMC article.

10

Cytotoxic diarylheptanoid induces cell cycle arrest and apoptosis via increasing ATF3 and stabilizing p53 in SH-SY5Y cells.

Tian Z, An N, Zhou B, Xiao P, Kohane IS, Wu E. Tian Z, et al. Cancer Chemother Pharmacol. 2009 May;63(6):1131-9. doi: 10.1007/s00280-008-0832-5. Epub 2008 Oct 3. Cancer Chemother Pharmacol. 2009. PMID: 18836721 Free PMC article.

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