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Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein.
Singh VP, Rubinstein J, Arvanitis DA, Ren X, Gao X, Haghighi K, Gilbert M, Iyer VR, Kim DH, Cho C, Jones K, Lorenz JN, Armstrong CF, Wang HS, Gyorke S, Kranias EG. Singh VP, et al. Among authors: arvanitis da. J Am Heart Assoc. 2013 Oct 14;2(5):e000460. doi: 10.1161/JAHA.113.000460. J Am Heart Assoc. 2013. PMID: 24125847 Free PMC article.
Histidine-rich Ca-binding protein interacts with sarcoplasmic reticulum Ca-ATPase.
Arvanitis DA, Vafiadaki E, Fan GC, Mitton BA, Gregory KN, Del Monte F, Kontrogianni-Konstantopoulos A, Sanoudou D, Kranias EG. Arvanitis DA, et al. Am J Physiol Heart Circ Physiol. 2007 Sep;293(3):H1581-9. doi: 10.1152/ajpheart.00278.2007. Epub 2007 May 25. Am J Physiol Heart Circ Physiol. 2007. PMID: 17526652 Free article.
Phosphorylation of serine96 of histidine-rich calcium-binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia.
Pollak AJ, Haghighi K, Kunduri S, Arvanitis DA, Bidwell PA, Liu GS, Singh VP, Gonzalez DJ, Sanoudou D, Wiley SE, Dixon JE, Kranias EG. Pollak AJ, et al. Among authors: arvanitis da. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9098-9103. doi: 10.1073/pnas.1706441114. Epub 2017 Aug 7. Proc Natl Acad Sci U S A. 2017. PMID: 28784772 Free PMC article.
Impaired calcium homeostasis is associated with sudden cardiac death and arrhythmias in a genetic equivalent mouse model of the human HRC-Ser96Ala variant.
Tzimas C, Johnson DM, Santiago DJ, Vafiadaki E, Arvanitis DA, Davos CH, Varela A, Athanasiadis NC, Dimitriou C, Katsimpoulas M, Sonntag S, Kryzhanovska M, Shmerling D, Lehnart SE, Sipido KR, Kranias EG, Sanoudou D. Tzimas C, et al. Among authors: arvanitis da. Cardiovasc Res. 2017 Sep 1;113(11):1403-1417. doi: 10.1093/cvr/cvx113. Cardiovasc Res. 2017. PMID: 28859293
The Ser96Ala variant in histidine-rich calcium-binding protein is associated with life-threatening ventricular arrhythmias in idiopathic dilated cardiomyopathy.
Arvanitis DA, Sanoudou D, Kolokathis F, Vafiadaki E, Papalouka V, Kontrogianni-Konstantopoulos A, Theodorakis GN, Paraskevaidis IA, Adamopoulos S, Dorn GW 2nd, Kremastinos DT, Kranias EG. Arvanitis DA, et al. Eur Heart J. 2008 Oct;29(20):2514-25. doi: 10.1093/eurheartj/ehn328. Epub 2008 Jul 9. Eur Heart J. 2008. PMID: 18617481 Free PMC article.
50 results