Shoemaker RH - Search Results

1

CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute.

Zoppoli G, Solier S, Reinhold WC, Liu H, Connelly JW Jr, Monks A, Shoemaker RH, Abaan OD, Davis SR, Meltzer PS, Doroshow JH, Pommier Y. Zoppoli G, et al. Among authors: shoemaker rh. Oncogene. 2012 Jan 26;31(4):403-18. doi: 10.1038/onc.2011.283. Epub 2011 Jul 18. Oncogene. 2012. PMID: 21765476 Free PMC article.

2

Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines.

Monks A, Scudiero D, Skehan P, Shoemaker R, Paull K, Vistica D, Hose C, Langley J, Cronise P, Vaigro-Wolff A, et al. Monks A, et al. J Natl Cancer Inst. 1991 Jun 5;83(11):757-66. doi: 10.1093/jnci/83.11.757. J Natl Cancer Inst. 1991. PMID: 2041050

3

Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines.

Rubinstein LV, Shoemaker RH, Paull KD, Simon RM, Tosini S, Skehan P, Scudiero DA, Monks A, Boyd MR. Rubinstein LV, et al. Among authors: shoemaker rh. J Natl Cancer Inst. 1990 Jul 4;82(13):1113-8. doi: 10.1093/jnci/82.13.1113. J Natl Cancer Inst. 1990. PMID: 2359137

4

Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm.

Paull KD, Shoemaker RH, Hodes L, Monks A, Scudiero DA, Rubinstein L, Plowman J, Boyd MR. Paull KD, et al. Among authors: shoemaker rh. J Natl Cancer Inst. 1989 Jul 19;81(14):1088-92. doi: 10.1093/jnci/81.14.1088. J Natl Cancer Inst. 1989. PMID: 2738938

5

Development of human tumor cell line panels for use in disease-oriented drug screening.

Shoemaker RH, Monks A, Alley MC, Scudiero DA, Fine DL, McLemore TL, Abbott BJ, Paull KD, Mayo JG, Boyd MR. Shoemaker RH, et al. Prog Clin Biol Res. 1988;276:265-86. Prog Clin Biol Res. 1988. PMID: 3051021 Review. No abstract available.

6

Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications.

Rapisarda A, Uranchimeg B, Sordet O, Pommier Y, Shoemaker RH, Melillo G. Rapisarda A, et al. Among authors: shoemaker rh. Cancer Res. 2004 Feb 15;64(4):1475-82. doi: 10.1158/0008-5472.can-03-3139. Cancer Res. 2004. PMID: 14983893

7

Identification of a Bis-guanylhydrazone [4,4'-Diacetyldiphenylurea-bis(guanylhydrazone); NSC 109555] as a novel chemotype for inhibition of Chk2 kinase.

Jobson AG, Cardellina JH 2nd, Scudiero D, Kondapaka S, Zhang H, Kim H, Shoemaker R, Pommier Y. Jobson AG, et al. Mol Pharmacol. 2007 Oct;72(4):876-84. doi: 10.1124/mol.107.035832. Epub 2007 Jul 6. Mol Pharmacol. 2007. PMID: 17616632

8

Crystal structure of checkpoint kinase 2 in complex with NSC 109555, a potent and selective inhibitor.

Lountos GT, Tropea JE, Zhang D, Jobson AG, Pommier Y, Shoemaker RH, Waugh DS. Lountos GT, et al. Among authors: shoemaker rh. Protein Sci. 2009 Jan;18(1):92-100. doi: 10.1002/pro.16. Protein Sci. 2009. PMID: 19177354 Free PMC article.

9

Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts.

Monks A, Hose CD, Pezzoli P, Kondapaka S, Vansant G, Petersen KD, Sehested M, Monforte J, Shoemaker RH. Monks A, et al. Among authors: shoemaker rh. Anticancer Drugs. 2009 Sep;20(8):682-92. doi: 10.1097/CAD.0b013e32832e14e1. Anticancer Drugs. 2009. PMID: 19606018

10

Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide].

Jobson AG, Lountos GT, Lorenzi PL, Llamas J, Connelly J, Cerna D, Tropea JE, Onda A, Zoppoli G, Kondapaka S, Zhang G, Caplen NJ, Cardellina JH 2nd, Yoo SS, Monks A, Self C, Waugh DS, Shoemaker RH, Pommier Y. Jobson AG, et al. Among authors: shoemaker rh. J Pharmacol Exp Ther. 2009 Dec;331(3):816-26. doi: 10.1124/jpet.109.154997. Epub 2009 Sep 9. J Pharmacol Exp Ther. 2009. PMID: 19741151 Free PMC article.

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