Genetic variation at a single locus and age of onset for Alzheimer's disease.
Lutz MW, Crenshaw DG, Saunders AM, Roses AD.
Lutz MW, et al. Among authors: saunders am.
Alzheimers Dement. 2010 Mar;6(2):125-31. doi: 10.1016/j.jalz.2010.01.011.
Alzheimers Dement. 2010.
PMID: 20298972
Free PMC article.
The significant finding discussed here is that a variable-length, deoxythymidine homopolymer (poly-T) within intron 6 of the TOMM40 gene is associated with the age of onset of LOAD [Roses AD, Lutz MW, Amrine-Madsen H, Saunders AM, Crenshaw DG, Sundseth SS, et al. A …
The significant finding discussed here is that a variable-length, deoxythymidine homopolymer (poly-T) within intron 6 of the TOMM40 gene is …