Agarwal S - Search Results

1

Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team up.

Agarwal S, Hartz AM, Elmquist WF, Bauer B. Agarwal S, et al. Curr Pharm Des. 2011;17(26):2793-802. doi: 10.2174/138161211797440186. Curr Pharm Des. 2011. PMID: 21827403 Free PMC article. Review.

2

P-glycoprotein and breast cancer resistance protein influence brain distribution of dasatinib.

Chen Y, Agarwal S, Shaik NM, Chen C, Yang Z, Elmquist WF. Chen Y, et al. Among authors: agarwal s. J Pharmacol Exp Ther. 2009 Sep;330(3):956-63. doi: 10.1124/jpet.109.154781. Epub 2009 Jun 2. J Pharmacol Exp Ther. 2009. PMID: 19491323

3

Distribution of gefitinib to the brain is limited by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)-mediated active efflux.

Agarwal S, Sane R, Gallardo JL, Ohlfest JR, Elmquist WF. Agarwal S, et al. J Pharmacol Exp Ther. 2010 Jul;334(1):147-55. doi: 10.1124/jpet.110.167601. Epub 2010 Apr 26. J Pharmacol Exp Ther. 2010. PMID: 20421331 Free PMC article.

4

The role of the breast cancer resistance protein (ABCG2) in the distribution of sorafenib to the brain.

Agarwal S, Sane R, Ohlfest JR, Elmquist WF. Agarwal S, et al. J Pharmacol Exp Ther. 2011 Jan;336(1):223-33. doi: 10.1124/jpet.110.175034. Epub 2010 Oct 15. J Pharmacol Exp Ther. 2011. PMID: 20952483 Free PMC article.

5

Delivery of molecularly targeted therapy to malignant glioma, a disease of the whole brain.

Agarwal S, Sane R, Oberoi R, Ohlfest JR, Elmquist WF. Agarwal S, et al. Expert Rev Mol Med. 2011 May 13;13:e17. doi: 10.1017/S1462399411001888. Expert Rev Mol Med. 2011. PMID: 21676290 Free PMC article. Review.

6

Brain distribution of cediranib is limited by active efflux at the blood-brain barrier.

Wang T, Agarwal S, Elmquist WF. Wang T, et al. Among authors: agarwal s. J Pharmacol Exp Ther. 2012 May;341(2):386-95. doi: 10.1124/jpet.111.190488. Epub 2012 Feb 8. J Pharmacol Exp Ther. 2012. PMID: 22323823 Free PMC article.

7

Insight into the cooperation of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) at the blood-brain barrier: a case study examining sorafenib efflux clearance.

Agarwal S, Elmquist WF. Agarwal S, et al. Mol Pharm. 2012 Mar 5;9(3):678-84. doi: 10.1021/mp200465c. Epub 2012 Feb 22. Mol Pharm. 2012. PMID: 22335402 Free PMC article.

8

Quantitative proteomics of transporter expression in brain capillary endothelial cells isolated from P-glycoprotein (P-gp), breast cancer resistance protein (Bcrp), and P-gp/Bcrp knockout mice.

Agarwal S, Uchida Y, Mittapalli RK, Sane R, Terasaki T, Elmquist WF. Agarwal S, et al. Drug Metab Dispos. 2012 Jun;40(6):1164-9. doi: 10.1124/dmd.112.044719. Epub 2012 Mar 8. Drug Metab Dispos. 2012. PMID: 22401960 Free PMC article.

9

Function of the blood-brain barrier and restriction of drug delivery to invasive glioma cells: findings in an orthotopic rat xenograft model of glioma.

Agarwal S, Manchanda P, Vogelbaum MA, Ohlfest JR, Elmquist WF. Agarwal S, et al. Drug Metab Dispos. 2013 Jan;41(1):33-9. doi: 10.1124/dmd.112.048322. Epub 2012 Sep 26. Drug Metab Dispos. 2013. PMID: 23014761 Free PMC article.

10

Brain metastases from renal cell carcinoma in the era of tyrosine kinase inhibitors.

Dudek AZ, Raza A, Chi M, Singhal M, Oberoi R, Mittapalli RK, Agarwal S, Elmquist WF. Dudek AZ, et al. Among authors: agarwal s. Clin Genitourin Cancer. 2013 Jun;11(2):155-60. doi: 10.1016/j.clgc.2012.11.001. Epub 2012 Dec 21. Clin Genitourin Cancer. 2013. PMID: 23265925 Free PMC article.

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