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Human mutation within Per-Arnt-Sim (PAS) domain-containing protein kinase (PASK) causes basal insulin hypersecretion.
Semplici F, Vaxillaire M, Fogarty S, Semache M, Bonnefond A, Fontés G, Philippe J, Meur G, Diraison F, Sessions RB, Rutter J, Poitout V, Froguel P, Rutter GA. Semplici F, et al. Among authors: rutter ga, rutter j. J Biol Chem. 2011 Dec 23;286(51):44005-44014. doi: 10.1074/jbc.M111.254995. Epub 2011 Nov 7. J Biol Chem. 2011. PMID: 22065581 Free PMC article.
Control of mammalian glycogen synthase by PAS kinase.
Wilson WA, Skurat AV, Probst B, de Paoli-Roach A, Roach PJ, Rutter J. Wilson WA, et al. Among authors: rutter j. Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16596-601. doi: 10.1073/pnas.0508481102. Epub 2005 Nov 7. Proc Natl Acad Sci U S A. 2005. PMID: 16275910 Free PMC article.
PAS kinase is required for normal cellular energy balance.
Hao HX, Cardon CM, Swiatek W, Cooksey RC, Smith TL, Wilde J, Boudina S, Abel ED, McClain DA, Rutter J. Hao HX, et al. Among authors: rutter j. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15466-71. doi: 10.1073/pnas.0705407104. Epub 2007 Sep 18. Proc Natl Acad Sci U S A. 2007. PMID: 17878307 Free PMC article.
Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization.
An R, da Silva Xavier G, Semplici F, Vakhshouri S, Hao HX, Rutter J, Pagano MA, Meggio F, Pinna LA, Rutter GA. An R, et al. Among authors: rutter ga, rutter j. Biochem Biophys Res Commun. 2010 Aug 20;399(2):155-61. doi: 10.1016/j.bbrc.2010.07.035. Epub 2010 Jul 15. Biochem Biophys Res Commun. 2010. PMID: 20637728 Free PMC article.
Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion.
da Silva Xavier G, Farhan H, Kim H, Caxaria S, Johnson P, Hughes S, Bugliani M, Marselli L, Marchetti P, Birzele F, Sun G, Scharfmann R, Rutter J, Siniakowicz K, Weir G, Parker H, Reimann F, Gribble FM, Rutter GA. da Silva Xavier G, et al. Among authors: rutter ga, rutter j. Diabetologia. 2011 Apr;54(4):819-27. doi: 10.1007/s00125-010-2010-7. Epub 2010 Dec 23. Diabetologia. 2011. PMID: 21181396 Free PMC article.
398 results