Semache M - Search Results

1

Human mutation within Per-Arnt-Sim (PAS) domain-containing protein kinase (PASK) causes basal insulin hypersecretion.

Semplici F, Vaxillaire M, Fogarty S, Semache M, Bonnefond A, Fontés G, Philippe J, Meur G, Diraison F, Sessions RB, Rutter J, Poitout V, Froguel P, Rutter GA. Semplici F, et al. Among authors: semache m. J Biol Chem. 2011 Dec 23;286(51):44005-44014. doi: 10.1074/jbc.M111.254995. Epub 2011 Nov 7. J Biol Chem. 2011. PMID: 22065581 Free PMC article.

2

Cyclical and alternating infusions of glucose and intralipid in rats inhibit insulin gene expression and Pdx-1 binding in islets.

Hagman DK, Latour MG, Chakrabarti SK, Fontes G, Amyot J, Tremblay C, Semache M, Lausier JA, Roskens V, Mirmira RG, Jetton TL, Poitout V. Hagman DK, et al. Among authors: semache m. Diabetes. 2008 Feb;57(2):424-31. doi: 10.2337/db07-1285. Epub 2007 Nov 8. Diabetes. 2008. PMID: 17991758 Free PMC article.

3

The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding.

Kebede M, Alquier T, Latour MG, Semache M, Tremblay C, Poitout V. Kebede M, et al. Among authors: semache m. Diabetes. 2008 Sep;57(9):2432-7. doi: 10.2337/db08-0553. Epub 2008 Jun 16. Diabetes. 2008. PMID: 18559658 Free PMC article.

4

Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells.

Fontés G, Semache M, Hagman DK, Tremblay C, Shah R, Rhodes CJ, Rutter J, Poitout V. Fontés G, et al. Among authors: semache m. Diabetes. 2009 Sep;58(9):2048-58. doi: 10.2337/db08-0579. Epub 2009 Jun 5. Diabetes. 2009. PMID: 19502418 Free PMC article.

5

Glucolipotoxicity of the pancreatic beta cell.

Poitout V, Amyot J, Semache M, Zarrouki B, Hagman D, Fontés G. Poitout V, et al. Among authors: semache m. Biochim Biophys Acta. 2010 Mar;1801(3):289-98. doi: 10.1016/j.bbalip.2009.08.006. Epub 2009 Aug 26. Biochim Biophys Acta. 2010. PMID: 19715772 Free PMC article. Review.

6

Lack of preservation of insulin gene expression by a glucagon-like peptide 1 agonist or a dipeptidyl peptidase 4 inhibitor in an in vivo model of glucolipotoxicity.

Fontés G, Hagman DK, Latour MG, Semache M, Poitout V. Fontés G, et al. Among authors: semache m. Diabetes Res Clin Pract. 2010 Mar;87(3):322-8. doi: 10.1016/j.diabres.2009.12.020. Epub 2010 Jan 25. Diabetes Res Clin Pract. 2010. PMID: 20092903 Free PMC article.

7

Glucolipotoxicity age-dependently impairs beta cell function in rats despite a marked increase in beta cell mass.

Fontés G, Zarrouki B, Hagman DK, Latour MG, Semache M, Roskens V, Moore PC, Prentki M, Rhodes CJ, Jetton TL, Poitout V. Fontés G, et al. Among authors: semache m. Diabetologia. 2010 Nov;53(11):2369-79. doi: 10.1007/s00125-010-1850-5. Epub 2010 Jul 14. Diabetologia. 2010. PMID: 20628728 Free PMC article.

8

Lipopolysaccharides impair insulin gene expression in isolated islets of Langerhans via Toll-Like Receptor-4 and NF-κB signalling.

Amyot J, Semache M, Ferdaoussi M, Fontés G, Poitout V. Amyot J, et al. Among authors: semache m. PLoS One. 2012;7(4):e36200. doi: 10.1371/journal.pone.0036200. Epub 2012 Apr 27. PLoS One. 2012. PMID: 22558381 Free PMC article.

9

Per-Arnt-Sim kinase regulates pancreatic duodenal homeobox-1 protein stability via phosphorylation of glycogen synthase kinase 3β in pancreatic β-cells.

Semache M, Zarrouki B, Fontés G, Fogarty S, Kikani C, Chawki MB, Rutter J, Poitout V. Semache M, et al. J Biol Chem. 2013 Aug 23;288(34):24825-33. doi: 10.1074/jbc.M113.495945. Epub 2013 Jul 12. J Biol Chem. 2013. PMID: 23853095 Free PMC article.

10

Pancreatic and duodenal homeobox-1 nuclear localization is regulated by glucose in dispersed rat islets but not in insulin-secreting cell lines.

Semache M, Ghislain J, Zarrouki B, Tremblay C, Poitout V. Semache M, et al. Islets. 2014;6(4):e982376. doi: 10.4161/19382014.2014.982376. Islets. 2014. PMID: 25437380 Free PMC article.

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