Lin RC - Search Results

1

A microRNA guide for clinicians and basic scientists: background and experimental techniques.

Bernardo BC, Charchar FJ, Lin RC, McMullen JR. Bernardo BC, et al. Among authors: lin rc. Heart Lung Circ. 2012 Mar;21(3):131-42. doi: 10.1016/j.hlc.2011.11.002. Epub 2011 Dec 8. Heart Lung Circ. 2012. PMID: 22154518 Review.

2

miRNA therapeutics: a new class of drugs with potential therapeutic applications in the heart.

Bernardo BC, Ooi JY, Lin RC, McMullen JR. Bernardo BC, et al. Among authors: lin rc. Future Med Chem. 2015;7(13):1771-92. doi: 10.4155/fmc.15.107. Epub 2015 Sep 24. Future Med Chem. 2015. PMID: 26399457 Review.

3

Phosphoinositide 3-kinase (PI3K(p110alpha)) directly regulates key components of the Z-disc and cardiac structure.

Waardenberg AJ, Bernardo BC, Ng DCH, Shepherd PR, Cemerlang N, Sbroggiò M, Wells CA, Dalrymple BP, Brancaccio M, Lin RCY, McMullen JR. Waardenberg AJ, et al. J Biol Chem. 2011 Sep 2;286(35):30837-30846. doi: 10.1074/jbc.M111.271684. Epub 2011 Jul 11. J Biol Chem. 2011. PMID: 21757757 Free PMC article.

4

Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function.

Bernardo BC, Gao XM, Winbanks CE, Boey EJ, Tham YK, Kiriazis H, Gregorevic P, Obad S, Kauppinen S, Du XJ, Lin RC, McMullen JR. Bernardo BC, et al. Among authors: lin rc. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17615-20. doi: 10.1073/pnas.1206432109. Epub 2012 Oct 9. Proc Natl Acad Sci U S A. 2012. PMID: 23047694 Free PMC article.

5

Silencing of miR-34a attenuates cardiac dysfunction in a setting of moderate, but not severe, hypertrophic cardiomyopathy.

Bernardo BC, Gao XM, Tham YK, Kiriazis H, Winbanks CE, Ooi JY, Boey EJ, Obad S, Kauppinen S, Gregorevic P, Du XJ, Lin RC, McMullen JR. Bernardo BC, et al. Among authors: lin rc. PLoS One. 2014 Feb 27;9(2):e90337. doi: 10.1371/journal.pone.0090337. eCollection 2014. PLoS One. 2014. PMID: 24587330 Free PMC article.

6

Therapeutic silencing of miR-652 restores heart function and attenuates adverse remodeling in a setting of established pathological hypertrophy.

Bernardo BC, Nguyen SS, Winbanks CE, Gao XM, Boey EJ, Tham YK, Kiriazis H, Ooi JY, Porrello ER, Igoor S, Thomas CJ, Gregorevic P, Lin RC, Du XJ, McMullen JR. Bernardo BC, et al. Among authors: lin rc. FASEB J. 2014 Dec;28(12):5097-110. doi: 10.1096/fj.14-253856. Epub 2014 Aug 21. FASEB J. 2014. PMID: 25145628

7

Inhibition of miR-154 Protects Against Cardiac Dysfunction and Fibrosis in a Mouse Model of Pressure Overload.

Bernardo BC, Nguyen SS, Gao XM, Tham YK, Ooi JY, Patterson NL, Kiriazis H, Su Y, Thomas CJ, Lin RC, Du XJ, McMullen JR. Bernardo BC, et al. Among authors: lin rc. Sci Rep. 2016 Mar 1;6:22442. doi: 10.1038/srep22442. Sci Rep. 2016. PMID: 26928825 Free PMC article.

8

Identification of miR-34 regulatory networks in settings of disease and antimiR-therapy: Implications for treating cardiac pathology and other diseases.

Ooi JYY, Bernardo BC, Singla S, Patterson NL, Lin RCY, McMullen JR. Ooi JYY, et al. RNA Biol. 2017 May 4;14(5):500-513. doi: 10.1080/15476286.2016.1181251. Epub 2016 Apr 28. RNA Biol. 2017. PMID: 27124358 Free PMC article.

9

Sex differences in response to miRNA-34a therapy in mouse models of cardiac disease: identification of sex-, disease- and treatment-regulated miRNAs.

Bernardo BC, Ooi JY, Matsumoto A, Tham YK, Singla S, Kiriazis H, Patterson NL, Sadoshima J, Obad S, Lin RC, McMullen JR. Bernardo BC, et al. Among authors: lin rc. J Physiol. 2016 Oct 15;594(20):5959-5974. doi: 10.1113/JP272512. Epub 2016 Jul 20. J Physiol. 2016. PMID: 27270487 Free PMC article.

10

PI3K(p110 alpha) protects against myocardial infarction-induced heart failure: identification of PI3K-regulated miRNA and mRNA.

Lin RC, Weeks KL, Gao XM, Williams RB, Bernardo BC, Kiriazis H, Matthews VB, Woodcock EA, Bouwman RD, Mollica JP, Speirs HJ, Dawes IW, Daly RJ, Shioi T, Izumo S, Febbraio MA, Du XJ, McMullen JR. Lin RC, et al. Arterioscler Thromb Vasc Biol. 2010 Apr;30(4):724-32. doi: 10.1161/ATVBAHA.109.201988. Arterioscler Thromb Vasc Biol. 2010. PMID: 20237330

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