Kern CB - Search Results

1

Maladaptive matrix remodeling and regional biomechanical dysfunction in a mouse model of aortic valve disease.

Krishnamurthy VK, Opoka AM, Kern CB, Guilak F, Narmoneva DA, Hinton RB. Krishnamurthy VK, et al. Among authors: kern cb. Matrix Biol. 2012 Apr;31(3):197-205. doi: 10.1016/j.matbio.2012.01.001. Epub 2012 Jan 12. Matrix Biol. 2012. PMID: 22265892 Free PMC article.

2

Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies.

Kern CB, Wessels A, McGarity J, Dixon LJ, Alston E, Argraves WS, Geeting D, Nelson CM, Menick DR, Apte SS. Kern CB, et al. Matrix Biol. 2010 May;29(4):304-16. doi: 10.1016/j.matbio.2010.01.005. Epub 2010 Jan 22. Matrix Biol. 2010. PMID: 20096780 Free PMC article.

3

Insufficient versican cleavage and Smad2 phosphorylation results in bicuspid aortic and pulmonary valves.

Dupuis LE, Osinska H, Weinstein MB, Hinton RB, Kern CB. Dupuis LE, et al. Among authors: kern cb. J Mol Cell Cardiol. 2013 Jul;60:50-9. doi: 10.1016/j.yjmcc.2013.03.010. Epub 2013 Mar 24. J Mol Cell Cardiol. 2013. PMID: 23531444 Free PMC article.

4

Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease.

Angel PM, Narmoneva DA, Sewell-Loftin MK, Munjal C, Dupuis L, Landis BJ, Jegga A, Kern CB, Merryman WD, Baldwin HS, Bressan GM, Hinton RB. Angel PM, et al. Among authors: kern cb. Ann Biomed Eng. 2017 Nov;45(11):2548-2562. doi: 10.1007/s10439-017-1899-0. Epub 2017 Aug 15. Ann Biomed Eng. 2017. PMID: 28812215 Free PMC article.

5

Truncation of the amino-terminus of the recombinant aggrecan rAgg1mut leads to reduced cleavage at the aggrecanase site. Efficient aggrecanase catabolism may depend on multiple substrate interactions.

Hörber C, Büttner FH, Kern C, Schmiedeknecht G, Bartnik E. Hörber C, et al. Matrix Biol. 2000 Nov;19(6):533-43. doi: 10.1016/s0945-053x(00)00113-x. Matrix Biol. 2000. PMID: 11068207

6

Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.

Dupuis LE, McCulloch DR, McGarity JD, Bahan A, Wessels A, Weber D, Diminich AM, Nelson CM, Apte SS, Kern CB. Dupuis LE, et al. Among authors: kern cb. Dev Biol. 2011 Sep 1;357(1):152-64. doi: 10.1016/j.ydbio.2011.06.041. Epub 2011 Jul 1. Dev Biol. 2011. PMID: 21749862 Free PMC article.

7

Versican accumulation drives Nos2 induction and aortic disease in Marfan syndrome via Akt activation.

Ruiz-Rodríguez MJ, Oller J, Martínez-Martínez S, Alarcón-Ruiz I, Toral M, Sun Y, Colmenar Á, Méndez-Olivares MJ, López-Maderuelo D, Kern CB, Nistal JF, Evangelista A, Teixido-Tura G, Campanero MR, Redondo JM. Ruiz-Rodríguez MJ, et al. Among authors: kern cb. EMBO Mol Med. 2024 Jan;16(1):132-157. doi: 10.1038/s44321-023-00009-7. Epub 2024 Jan 2. EMBO Mol Med. 2024. PMID: 38177536 Free PMC article.

8

Cartilage link protein 1 (Crtl1), an extracellular matrix component playing an important role in heart development.

Wirrig EE, Snarr BS, Chintalapudi MR, O'neal JL, Phelps AL, Barth JL, Fresco VM, Kern CB, Mjaatvedt CH, Toole BP, Hoffman S, Trusk TC, Argraves WS, Wessels A. Wirrig EE, et al. Among authors: kern cb. Dev Biol. 2007 Oct 15;310(2):291-303. doi: 10.1016/j.ydbio.2007.07.041. Epub 2007 Aug 9. Dev Biol. 2007. PMID: 17822691 Free PMC article.

9

Adamts5^-/- Mice Exhibit Altered Aggrecan Proteolytic Profiles That Correlate With Ascending Aortic Anomalies.

Dupuis LE, Nelson EL, Hozik B, Porto SC, Rogers-DeCotes A, Fosang A, Kern CB. Dupuis LE, et al. Among authors: kern cb. Arterioscler Thromb Vasc Biol. 2019 Oct;39(10):2067-2081. doi: 10.1161/ATVBAHA.119.313077. Epub 2019 Aug 1. Arterioscler Thromb Vasc Biol. 2019. PMID: 31366218 Free PMC article.

10

Identification and detection of the periostin gene in cardiac development.

Norris RA, Kern CB, Wessels A, Moralez EI, Markwald RR, Mjaatvedt CH. Norris RA, et al. Among authors: kern cb. Anat Rec A Discov Mol Cell Evol Biol. 2004 Dec;281(2):1227-33. doi: 10.1002/ar.a.20135. Anat Rec A Discov Mol Cell Evol Biol. 2004. PMID: 15532025 Free article.

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