Kozikowski AP - Search Results

1

Derivatives of 3-isoxazolecarboxylic acid esters: a potent and selective compound class against replicating and nonreplicating Mycobacterium tuberculosis.

Lilienkampf A, Pieroni M, Franzblau SG, Bishai WR, Kozikowski AP. Lilienkampf A, et al. Among authors: kozikowski ap. Curr Top Med Chem. 2012;12(7):729-34. doi: 10.2174/156802612799984544. Curr Top Med Chem. 2012. PMID: 22283815 Review.

2

Modification of the side chain of micromolide, an anti-tuberculosis natural product.

Yuan H, He R, Wan B, Wang Y, Pauli GF, Franzblau SG, Kozikowski AP. Yuan H, et al. Among authors: kozikowski ap. Bioorg Med Chem Lett. 2008 Oct 1;18(19):5311-5. doi: 10.1016/j.bmcl.2008.08.027. Epub 2008 Aug 14. Bioorg Med Chem Lett. 2008. PMID: 18774716

3

Structure-activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase.

Mao J, Eoh H, He R, Wang Y, Wan B, Franzblau SG, Crick DC, Kozikowski AP. Mao J, et al. Among authors: kozikowski ap. Bioorg Med Chem Lett. 2008 Oct 1;18(19):5320-3. doi: 10.1016/j.bmcl.2008.08.034. Epub 2008 Aug 14. Bioorg Med Chem Lett. 2008. PMID: 18783951 Free PMC article.

4

Structure-activity relationships for a series of quinoline-based compounds active against replicating and nonreplicating Mycobacterium tuberculosis.

Lilienkampf A, Mao J, Wan B, Wang Y, Franzblau SG, Kozikowski AP. Lilienkampf A, et al. Among authors: kozikowski ap. J Med Chem. 2009 Apr 9;52(7):2109-18. doi: 10.1021/jm900003c. J Med Chem. 2009. PMID: 19271749

5

Synthesis, biological evaluation, and structure-activity relationships for 5-[(E)-2-arylethenyl]-3-isoxazolecarboxylic acid alkyl ester derivatives as valuable antitubercular chemotypes.

Pieroni M, Lilienkampf A, Wan B, Wang Y, Franzblau SG, Kozikowski AP. Pieroni M, et al. Among authors: kozikowski ap. J Med Chem. 2009 Oct 22;52(20):6287-96. doi: 10.1021/jm900513a. J Med Chem. 2009. PMID: 19757815

6

Natural product leads for drug discovery: isolation, synthesis and biological evaluation of 6-cyano-5-methoxyindolo[2,3-a]carbazole based ligands as antibacterial agents.

Guo S, Tipparaju SK, Pegan SD, Wan B, Mo S, Orjala J, Mesecar AD, Franzblau SG, Kozikowski AP. Guo S, et al. Among authors: kozikowski ap. Bioorg Med Chem. 2009 Oct 15;17(20):7126-30. doi: 10.1016/j.bmc.2009.08.061. Epub 2009 Sep 4. Bioorg Med Chem. 2009. PMID: 19783449 Free PMC article.

7

Searching for new cures for tuberculosis: design, synthesis, and biological evaluation of 2-methylbenzothiazoles.

Huang Q, Mao J, Wan B, Wang Y, Brun R, Franzblau SG, Kozikowski AP. Huang Q, et al. Among authors: kozikowski ap. J Med Chem. 2009 Nov 12;52(21):6757-67. doi: 10.1021/jm901112f. J Med Chem. 2009. PMID: 19817445

8

From serendipity to rational antituberculosis drug discovery of mefloquine-isoxazole carboxylic acid esters.

Mao J, Yuan H, Wang Y, Wan B, Pieroni M, Huang Q, van Breemen RB, Kozikowski AP, Franzblau SG. Mao J, et al. Among authors: kozikowski ap. J Med Chem. 2009 Nov 26;52(22):6966-78. doi: 10.1021/jm900340a. J Med Chem. 2009. PMID: 19863050

9

Identification, synthesis, and pharmacological evaluation of tetrahydroindazole based ligands as novel antituberculosis agents.

Guo S, Song Y, Huang Q, Yuan H, Wan B, Wang Y, He R, Beconi MG, Franzblau SG, Kozikowski AP. Guo S, et al. Among authors: kozikowski ap. J Med Chem. 2010 Jan 28;53(2):649-59. doi: 10.1021/jm901235p. J Med Chem. 2010. PMID: 20000470

10

Rational design of 5-phenyl-3-isoxazolecarboxylic acid ethyl esters as growth inhibitors of Mycobacterium tuberculosis. a potent and selective series for further drug development.

Lilienkampf A, Pieroni M, Wan B, Wang Y, Franzblau SG, Kozikowski AP. Lilienkampf A, et al. Among authors: kozikowski ap. J Med Chem. 2010 Jan 28;53(2):678-88. doi: 10.1021/jm901273n. J Med Chem. 2010. PMID: 20000577

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