Dickerson TJ - Search Results

1

A coincidence detector triggers botulinum neurotoxin translocation.

Caglič D, Dickerson TJ. Caglič D, et al. Among authors: dickerson tj. Future Microbiol. 2012 Feb;7(2):185-8. doi: 10.2217/fmb.11.157. Future Microbiol. 2012. PMID: 22324987 Free PMC article.

2

Identification of clinically viable quinolinol inhibitors of botulinum neurotoxin A light chain.

Caglič D, Krutein MC, Bompiani KM, Barlow DJ, Benoni G, Pelletier JC, Reitz AB, Lairson LL, Houseknecht KL, Smith GR, Dickerson TJ. Caglič D, et al. Among authors: dickerson tj. J Med Chem. 2014 Feb 13;57(3):669-76. doi: 10.1021/jm4012164. Epub 2014 Jan 15. J Med Chem. 2014. PMID: 24387280 Free PMC article.

3

A high-throughput-compatible FRET-based platform for identification and characterization of botulinum neurotoxin light chain modulators.

Caglič D, Bompiani KM, Krutein MC, Čapek P, Dickerson TJ. Caglič D, et al. Among authors: dickerson tj. J Vis Exp. 2013 Dec 27;(82):50908. doi: 10.3791/50908. J Vis Exp. 2013. PMID: 24430674 Free PMC article.

4

High-Throughput Screening Uncovers Novel Botulinum Neurotoxin Inhibitor Chemotypes.

Bompiani KM, Caglič D, Krutein MC, Benoni G, Hrones M, Lairson LL, Bian H, Smith GR, Dickerson TJ. Bompiani KM, et al. Among authors: dickerson tj. ACS Comb Sci. 2016 Aug 8;18(8):461-74. doi: 10.1021/acscombsci.6b00033. Epub 2016 Jul 20. ACS Comb Sci. 2016. PMID: 27314875

5

Reexamining hydroxamate inhibitors of botulinum neurotoxin serotype A: extending towards the β-exosite.

Smith GR, Caglič D, Capek P, Zhang Y, Godbole S, Reitz AB, Dickerson TJ. Smith GR, et al. Among authors: dickerson tj. Bioorg Med Chem Lett. 2012 Jun 1;22(11):3754-7. doi: 10.1016/j.bmcl.2012.04.019. Epub 2012 Apr 11. Bioorg Med Chem Lett. 2012. PMID: 22542019 Free PMC article.

6

Investigating novel therapeutic targets and molecular mechanisms to treat botulinum neurotoxin A intoxication.

Eubanks LM, Dickerson TJ. Eubanks LM, et al. Among authors: dickerson tj. Future Microbiol. 2007 Dec;2(6):677-87. doi: 10.2217/17460913.2.6.677. Future Microbiol. 2007. PMID: 18041908

7

Enhancing the Pharmacokinetic Properties of Botulinum Neurotoxin Serotype A Protease Inhibitors Through Rational Design.

Capek P, Zhang Y, Barlow DJ, Houseknecht KL, Smith GR, Dickerson TJ. Capek P, et al. Among authors: dickerson tj. ACS Chem Neurosci. 2011 Jun 15;2(6):288-293. doi: 10.1021/cn200021q. ACS Chem Neurosci. 2011. PMID: 21743830 Free PMC article.

8

Sensing the deadliest toxin: technologies for botulinum neurotoxin detection.

Capek P, Dickerson TJ. Capek P, et al. Among authors: dickerson tj. Toxins (Basel). 2010 Jan;2(1):24-53. doi: 10.3390/toxins2020024. Epub 2010 Jan 7. Toxins (Basel). 2010. PMID: 22069545 Free PMC article.

9

The use of small molecules to investigate molecular mechanisms and therapeutic targets for treatment of botulinum neurotoxin A intoxication.

Dickerson TJ, Janda KD. Dickerson TJ, et al. ACS Chem Biol. 2006 Jul 21;1(6):359-69. doi: 10.1021/cb600179d. ACS Chem Biol. 2006. PMID: 17163773 Review.

10

The strange case of the botulinum neurotoxin: using chemistry and biology to modulate the most deadly poison.

Willis B, Eubanks LM, Dickerson TJ, Janda KD. Willis B, et al. Among authors: dickerson tj. Angew Chem Int Ed Engl. 2008;47(44):8360-79. doi: 10.1002/anie.200705531. Angew Chem Int Ed Engl. 2008. PMID: 18844202 Review.

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