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Potent inhibitors of 5-lipoxygenase identified using pseudoreceptors.
Rödl CB, Tanrikulu Y, Wisniewska JM, Proschak E, Schneider G, Steinhilber D, Hofmann B. Rödl CB, et al. ChemMedChem. 2011 Jun 6;6(6):1001-5. doi: 10.1002/cmdc.201100059. Epub 2011 Apr 19. ChemMedChem. 2011. PMID: 21506275 No abstract available.
Molecular pharmacological profile of a novel thiazolinone-based direct and selective 5-lipoxygenase inhibitor.
Hofmann B, Rödl CB, Kahnt AS, Maier TJ, Michel AA, Hoffmann M, Rau O, Awwad K, Pellowska M, Wurglics M, Wacker M, Zivković A, Fleming I, Schubert-Zsilavecz M, Stark H, Schneider G, Steinhilber D. Hofmann B, et al. Among authors: rodl cb. Br J Pharmacol. 2012 Apr;165(7):2304-13. doi: 10.1111/j.1476-5381.2011.01707.x. Br J Pharmacol. 2012. PMID: 21955369 Free PMC article.
Inhibition of 5-lipoxygenase by U73122 is due to covalent binding to cysteine 416.
Hörnig M, Markoutsa S, Häfner AK, George S, Wisniewska JM, Rödl CB, Hofmann B, Maier T, Karas M, Werz O, Steinhilber D. Hörnig M, et al. Among authors: rodl cb. Biochim Biophys Acta. 2012 Feb;1821(2):279-86. doi: 10.1016/j.bbalip.2011.11.001. Epub 2011 Nov 23. Biochim Biophys Acta. 2012. PMID: 22137889
Exploring the chemical space of multitarget ligands using aligned self-organizing maps.
Achenbach J, Klingler FM, Blöcher R, Moser D, Häfner AK, Rödl CB, Kretschmer S, Krüger B, Löhr F, Stark H, Hofmann B, Steinhilber D, Proschak E. Achenbach J, et al. Among authors: rodl cb. ACS Med Chem Lett. 2013 Oct 23;4(12):1169-72. doi: 10.1021/ml4002562. eCollection 2013 Dec 12. ACS Med Chem Lett. 2013. PMID: 24900624 Free PMC article.
14 results