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18 results

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Page 1
Genetic loss of insulin receptors worsens cardiac efficiency in diabetes.
Bugger H, Riehle C, Jaishy B, Wende AR, Tuinei J, Chen D, Soto J, Pires KM, Boudina S, Theobald HA, Luptak I, Wayment B, Wang X, Litwin SE, Weimer BC, Abel ED. Bugger H, et al. Among authors: tuinei j. J Mol Cell Cardiol. 2012 May;52(5):1019-26. doi: 10.1016/j.yjmcc.2012.02.001. Epub 2012 Feb 9. J Mol Cell Cardiol. 2012. PMID: 22342406 Free PMC article.
Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes.
Wende AR, O'Neill BT, Bugger H, Riehle C, Tuinei J, Buchanan J, Tsushima K, Wang L, Caro P, Guo A, Sloan C, Kim BJ, Wang X, Pereira RO, McCrory MA, Nye BG, Benavides GA, Darley-Usmar VM, Shioi T, Weimer BC, Abel ED. Wende AR, et al. Among authors: tuinei j. Mol Cell Biol. 2015 Mar;35(5):831-46. doi: 10.1128/MCB.01109-14. Epub 2014 Dec 22. Mol Cell Biol. 2015. PMID: 25535334 Free PMC article.
Antioxidant treatment normalizes mitochondrial energetics and myocardial insulin sensitivity independently of changes in systemic metabolic homeostasis in a mouse model of the metabolic syndrome.
Ilkun O, Wilde N, Tuinei J, Pires KM, Zhu Y, Bugger H, Soto J, Wayment B, Olsen C, Litwin SE, Abel ED. Ilkun O, et al. Among authors: tuinei j. J Mol Cell Cardiol. 2015 Aug;85:104-16. doi: 10.1016/j.yjmcc.2015.05.012. Epub 2015 May 22. J Mol Cell Cardiol. 2015. PMID: 26004364 Free PMC article.
A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy.
O'Neill BT, Kim J, Wende AR, Theobald HA, Tuinei J, Buchanan J, Guo A, Zaha VG, Davis DK, Schell JC, Boudina S, Wayment B, Litwin SE, Shioi T, Izumo S, Birnbaum MJ, Abel ED. O'Neill BT, et al. Among authors: tuinei j. Cell Metab. 2007 Oct;6(4):294-306. doi: 10.1016/j.cmet.2007.09.001. Cell Metab. 2007. PMID: 17908558 Free PMC article.
Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses.
Wende AR, Kim J, Holland WL, Wayment BE, O'Neill BT, Tuinei J, Brahma MK, Pepin ME, McCrory MA, Luptak I, Halade GV, Litwin SE, Abel ED. Wende AR, et al. Among authors: tuinei j. Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1098-H1108. doi: 10.1152/ajpheart.00101.2017. Epub 2017 Aug 19. Am J Physiol Heart Circ Physiol. 2017. PMID: 28822962 Free PMC article.
Maintaining Myocardial Glucose Utilization in Diabetic Cardiomyopathy Accelerates Mitochondrial Dysfunction.
Wende AR, Schell JC, Ha CM, Pepin ME, Khalimonchuk O, Schwertz H, Pereira RO, Brahma MK, Tuinei J, Contreras-Ferrat A, Wang L, Andrizzi CA, Olsen CD, Bradley WE, Dell'Italia LJ, Dillmann WH, Litwin SE, Abel ED. Wende AR, et al. Among authors: tuinei j. Diabetes. 2020 Oct;69(10):2094-2111. doi: 10.2337/db19-1057. Epub 2020 May 4. Diabetes. 2020. PMID: 32366681 Free PMC article.
18 results