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The mycobacterial acyltransferase PapA5 is required for biosynthesis of cell wall-associated phenolic glycolipids.
Microbiology (Reading). 2012 May;158(Pt 5):1379-1387. doi: 10.1099/mic.0.057869-0. Epub 2012 Feb 23.
Microbiology (Reading). 2012.
PMID: 22361940
Free PMC article.
Mycobacterial polyketide-associated proteins are acyltransferases: proof of principle with Mycobacterium tuberculosis PapA5.
Onwueme KC, Ferreras JA, Buglino J, Lima CD, Quadri LE.
Onwueme KC, et al.
Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4608-13. doi: 10.1073/pnas.0306928101. Epub 2004 Mar 18.
Proc Natl Acad Sci U S A. 2004.
PMID: 15070765
Free PMC article.
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Identification of phthiodiolone ketoreductase, an enzyme required for production of mycobacterial diacyl phthiocerol virulence factors.
Onwueme KC, Vos CJ, Zurita J, Soll CE, Quadri LE.
Onwueme KC, et al.
J Bacteriol. 2005 Jul;187(14):4760-6. doi: 10.1128/JB.187.14.4760-4766.2005.
J Bacteriol. 2005.
PMID: 15995190
Free PMC article.
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Crystal structure of PapA5, a phthiocerol dimycocerosyl transferase from Mycobacterium tuberculosis.
Buglino J, Onwueme KC, Ferreras JA, Quadri LE, Lima CD.
Buglino J, et al. Among authors: onwueme kc.
J Biol Chem. 2004 Jul 16;279(29):30634-42. doi: 10.1074/jbc.M404011200. Epub 2004 May 3.
J Biol Chem. 2004.
PMID: 15123643
Free article.
Item in Clipboard
The dimycocerosate ester polyketide virulence factors of mycobacteria.
Onwueme KC, Vos CJ, Zurita J, Ferreras JA, Quadri LE.
Onwueme KC, et al.
Prog Lipid Res. 2005 Sep;44(5):259-302. doi: 10.1016/j.plipres.2005.07.001. Epub 2005 Aug 3.
Prog Lipid Res. 2005.
PMID: 16115688
Review.
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Understanding and exploiting nature's chemical arsenal: the past, present and future of calicheamicin research.
Thorson JS, Sievers EL, Ahlert J, Shepard E, Whitwam RE, Onwueme KC, Ruppen M.
Thorson JS, et al. Among authors: onwueme kc.
Curr Pharm Des. 2000 Dec;6(18):1841-79. doi: 10.2174/1381612003398564.
Curr Pharm Des. 2000.
PMID: 11102565
Review.
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Resistance to enediyne antitumor antibiotics by CalC self-sacrifice.
Biggins JB, Onwueme KC, Thorson JS.
Biggins JB, et al. Among authors: onwueme kc.
Science. 2003 Sep 12;301(5639):1537-41. doi: 10.1126/science.1086695.
Science. 2003.
PMID: 12970566
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