Novick P - Search Results

1

Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'.

Levin AM, Bates DL, Ring AM, Krieg C, Lin JT, Su L, Moraga I, Raeber ME, Bowman GR, Novick P, Pande VS, Fathman CG, Boyman O, Garcia KC. Levin AM, et al. Among authors: novick p. Nature. 2012 Mar 25;484(7395):529-33. doi: 10.1038/nature10975. Nature. 2012. PMID: 22446627 Free PMC article.

2

Design of β-amyloid aggregation inhibitors from a predicted structural motif.

Novick PA, Lopes DH, Branson KM, Esteras-Chopo A, Graef IA, Bitan G, Pande VS. Novick PA, et al. J Med Chem. 2012 Apr 12;55(7):3002-10. doi: 10.1021/jm201332p. Epub 2012 Mar 15. J Med Chem. 2012. PMID: 22420626 Free PMC article.

3

SWEETLEAD: an in silico database of approved drugs, regulated chemicals, and herbal isolates for computer-aided drug discovery.

Novick PA, Ortiz OF, Poelman J, Abdulhay AY, Pande VS. Novick PA, et al. PLoS One. 2013 Nov 1;8(11):e79568. doi: 10.1371/journal.pone.0079568. eCollection 2013. PLoS One. 2013. PMID: 24223973 Free PMC article.

4

Rationally designed turn promoting mutation in the amyloid-β peptide sequence stabilizes oligomers in solution.

Rajadas J, Liu CW, Novick P, Kelley NW, Inayathullah M, Lemieux MC, Pande VS. Rajadas J, et al. Among authors: novick p. PLoS One. 2011;6(7):e21776. doi: 10.1371/journal.pone.0021776. Epub 2011 Jul 22. PLoS One. 2011. PMID: 21799748 Free PMC article.

5

Marked difference in saxitoxin and tetrodotoxin affinity for the human nociceptive voltage-gated sodium channel (Nav1.7) [corrected].

Walker JR, Novick PA, Parsons WH, McGregor M, Zablocki J, Pande VS, Du Bois J. Walker JR, et al. Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):18102-7. doi: 10.1073/pnas.1206952109. Epub 2012 Oct 17. Proc Natl Acad Sci U S A. 2012. PMID: 23077250 Free PMC article.

6

Bayesian analysis of isothermal titration calorimetry for binding thermodynamics.

Nguyen TH, Rustenburg AS, Krimmer SG, Zhang H, Clark JD, Novick PA, Branson K, Pande VS, Chodera JD, Minh DDL. Nguyen TH, et al. PLoS One. 2018 Sep 13;13(9):e0203224. doi: 10.1371/journal.pone.0203224. eCollection 2018. PLoS One. 2018. PMID: 30212471 Free PMC article.

7

A Targeted Computational Screen of the SWEETLEAD Database Reveals FDA-Approved Compounds with Anti-Dengue Viral Activity.

Moshiri J, Constant DA, Liu B, Mateo R, Kearnes S, Novick P, Prasad R, Nagamine C, Pande V, Kirkegaard K. Moshiri J, et al. Among authors: novick p. mBio. 2020 Nov 10;11(6):e02839-20. doi: 10.1128/mBio.02839-20. mBio. 2020. PMID: 33173007 Free PMC article.

8

Identification of Orai1 channel inhibitors by using minimal functional domains to screen small molecule microarrays.

Sadaghiani AM, Lee SM, Odegaard JI, Leveson-Gower DB, McPherson OM, Novick P, Kim MR, Koehler AN, Negrin R, Dolmetsch RE, Park CY. Sadaghiani AM, et al. Among authors: novick p. Chem Biol. 2014 Oct 23;21(10):1278-1292. doi: 10.1016/j.chembiol.2014.08.016. Epub 2014 Oct 9. Chem Biol. 2014. PMID: 25308275

9

Repurposing Carvedilol as a Novel Inhibitor of the Trypanosoma cruzi Autophagy Flux That Affects Parasite Replication and Survival.

Rivero CV, Martínez SJ, Novick P, Cueto JA, Salassa BN, Vanrell MC, Li X, Labriola CA, Polo LM, Engman DM, Clos J, Romano PS. Rivero CV, et al. Among authors: novick p. Front Cell Infect Microbiol. 2021 Aug 12;11:657257. doi: 10.3389/fcimb.2021.657257. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34476220 Free PMC article.

10

Different ER-plasma membrane tethers play opposing roles in autophagy of the cortical ER.

Liu D, Yuan H, Chen S, Ferro-Novick S, Novick P. Liu D, et al. Among authors: novick p. Proc Natl Acad Sci U S A. 2024 Jun 11;121(24):e2321991121. doi: 10.1073/pnas.2321991121. Epub 2024 Jun 5. Proc Natl Acad Sci U S A. 2024. PMID: 38838012

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