Sabio M - Search Results

1

4-(1-Phenyl-1H-pyrazol-4-yl)quinolines as novel, selective and brain penetrant metabotropic glutamate receptor 4 positive allosteric modulators.

Jimenez HN, Liu KG, Hong SP, Reitman MS, Uberti MA, Bacolod MD, Cajina M, Nattini M, Sabio M, Doller D. Jimenez HN, et al. Among authors: sabio m. Bioorg Med Chem Lett. 2012 May 1;22(9):3235-9. doi: 10.1016/j.bmcl.2012.03.032. Epub 2012 Mar 15. Bioorg Med Chem Lett. 2012. PMID: 22465637

2

Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators.

Hong SP, Liu KG, Ma G, Sabio M, Uberti MA, Bacolod MD, Peterson J, Zou ZZ, Robichaud AJ, Doller D. Hong SP, et al. Among authors: sabio m. J Med Chem. 2011 Jul 28;54(14):5070-81. doi: 10.1021/jm200290z. Epub 2011 Jul 1. J Med Chem. 2011. PMID: 21688779

3

Exploration of structure-based drug design opportunities for mGluRs.

Topiol S, Sabio M, Uberti M. Topiol S, et al. Among authors: sabio m. Neuropharmacology. 2011 Jan;60(1):93-101. doi: 10.1016/j.neuropharm.2010.08.001. Epub 2010 Aug 10. Neuropharmacology. 2011. PMID: 20705075

4

cis-1-Oxo-heterocyclyl-4-amido cyclohexane derivatives as NPY5 receptor antagonists.

Burns JF, Chen B, Chen CA, Doller D, Edelmenky E, Jiang Y, Peterson JM, Sabio M, Weiss J, White AD, Wu L, Bhardwaj R, Chandrasena G, Boyle NJ, Huang X. Burns JF, et al. Among authors: sabio m. Bioorg Med Chem Lett. 2014 Mar 15;24(6):1458-61. doi: 10.1016/j.bmcl.2014.02.023. Epub 2014 Feb 15. Bioorg Med Chem Lett. 2014. PMID: 24582476

5

Development of an aequorin luminescence calcium assay for high-throughput screening using a plate reader, the LumiLux.

Menon V, Ranganathn A, Jorgensen VH, Sabio M, Christoffersen CT, Uberti MA, Jones KA, Babu PS. Menon V, et al. Among authors: sabio m. Assay Drug Dev Technol. 2008 Dec;6(6):787-93. doi: 10.1089/adt.2008.157. Assay Drug Dev Technol. 2008. PMID: 19090690

6

Use of the X-ray structure of the Beta2-adrenergic receptor for drug discovery.

Topiol S, Sabio M. Topiol S, et al. Among authors: sabio m. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1598-602. doi: 10.1016/j.bmcl.2008.01.063. Epub 2008 Jan 19. Bioorg Med Chem Lett. 2008. PMID: 18243704

7

7TM X-ray structures for class C GPCRs as new drug-discovery tools. 1. mGluR5.

Topiol S, Sabio M. Topiol S, et al. Among authors: sabio m. Bioorg Med Chem Lett. 2016 Jan 15;26(2):484-494. doi: 10.1016/j.bmcl.2015.11.087. Epub 2015 Nov 25. Bioorg Med Chem Lett. 2016. PMID: 26706173

8

Use of the X-ray structure of the beta2-adrenergic receptor for drug discovery. Part 2: Identification of active compounds.

Sabio M, Jones K, Topiol S. Sabio M, et al. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5391-5. doi: 10.1016/j.bmcl.2008.09.046. Epub 2008 Sep 14. Bioorg Med Chem Lett. 2008. PMID: 18829308

9

1,4-Diazepane-2-ones as novel inhibitors of LFA-1.

Wattanasin S, Albert R, Ehrhardt C, Roche D, Sabio M, Hommel U, Welzenbach K, Weitz-Schmidt G. Wattanasin S, et al. Among authors: sabio m. Bioorg Med Chem Lett. 2003 Feb 10;13(3):499-502. doi: 10.1016/s0960-894x(02)00991-5. Bioorg Med Chem Lett. 2003. PMID: 12565959

10

Design and synthesis of potent and selective inhibitors of integrin VLA-4.

Wattanasin S, Weidmann B, Roche D, Myers S, Xing A, Guo Q, Sabio M, von Matt P, Hugo R, Maida S, Lake P, Weetall M. Wattanasin S, et al. Among authors: sabio m. Bioorg Med Chem Lett. 2001 Nov 19;11(22):2955-8. doi: 10.1016/s0960-894x(01)00586-8. Bioorg Med Chem Lett. 2001. PMID: 11677134

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