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Contribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variants.
Yedidi RS, Proteasa G, Martinez JL, Vickrey JF, Martin PD, Wawrzak Z, Liu Z, Kovari IA, Kovari LC. Yedidi RS, et al. Among authors: liu z. Acta Crystallogr D Biol Crystallogr. 2011 Jun;67(Pt 6):524-32. doi: 10.1107/S0907444911011541. Epub 2011 May 17. Acta Crystallogr D Biol Crystallogr. 2011. PMID: 21636892 Free PMC article.
The higher barrier of darunavir and tipranavir resistance for HIV-1 protease.
Wang Y, Liu Z, Brunzelle JS, Kovari IA, Dewdney TG, Reiter SJ, Kovari LC. Wang Y, et al. Among authors: liu z. Biochem Biophys Res Commun. 2011 Sep 9;412(4):737-42. doi: 10.1016/j.bbrc.2011.08.045. Epub 2011 Aug 17. Biochem Biophys Res Commun. 2011. PMID: 21871444 Free PMC article.
Design, synthesis and evaluation of a potent substrate analog inhibitor identified by scanning Ala/Phe mutagenesis, mimicking substrate co-evolution, against multidrug-resistant HIV-1 protease.
Yedidi RS, Muhuhi JM, Liu Z, Bencze KZ, Koupparis K, O'Connor CE, Kovari IA, Spaller MR, Kovari LC. Yedidi RS, et al. Among authors: liu z. Biochem Biophys Res Commun. 2013 Sep 6;438(4):703-8. doi: 10.1016/j.bbrc.2013.07.117. Epub 2013 Aug 3. Biochem Biophys Res Commun. 2013. PMID: 23921229 Free PMC article.
P1 and P1' para-fluoro phenyl groups show enhanced binding and favorable predicted pharmacological properties: structure-based virtual screening of extended lopinavir analogs against multi-drug resistant HIV-1 protease.
Yedidi RS, Liu Z, Kovari IA, Woster PM, Kovari LC. Yedidi RS, et al. Among authors: liu z. J Mol Graph Model. 2014 Feb;47:18-24. doi: 10.1016/j.jmgm.2013.10.010. Epub 2013 Nov 1. J Mol Graph Model. 2014. PMID: 24291501 Free PMC article.
88,240 results
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