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Rapid generation of functional dopaminergic neurons from human induced pluripotent stem cells through a single-step procedure using cell lineage transcription factors.
Theka I, Caiazzo M, Dvoretskova E, Leo D, Ungaro F, Curreli S, Managò F, Dell'Anno MT, Pezzoli G, Gainetdinov RR, Dityatev A, Broccoli V. Theka I, et al. Among authors: manago f. Stem Cells Transl Med. 2013 Jun;2(6):473-9. doi: 10.5966/sctm.2012-0133. Epub 2013 May 8. Stem Cells Transl Med. 2013. PMID: 23658252 Free PMC article.
SINEUP Non-coding RNA Targeting GDNF Rescues Motor Deficits and Neurodegeneration in a Mouse Model of Parkinson's Disease.
Espinoza S, Scarpato M, Damiani D, Managò F, Mereu M, Contestabile A, Peruzzo O, Carninci P, Santoro C, Papaleo F, Mingozzi F, Ronzitti G, Zucchelli S, Gustincich S. Espinoza S, et al. Among authors: manago f. Mol Ther. 2020 Feb 5;28(2):642-652. doi: 10.1016/j.ymthe.2019.08.005. Epub 2019 Aug 16. Mol Ther. 2020. PMID: 31495777 Free PMC article.
COMT Genetic Reduction Produces Sexually Divergent Effects on Cortical Anatomy and Working Memory in Mice and Humans.
Sannino S, Gozzi A, Cerasa A, Piras F, Scheggia D, Managò F, Damiano M, Galbusera A, Erickson LC, De Pietri Tonelli D, Bifone A, Tsaftaris SA, Caltagirone C, Weinberger DR, Spalletta G, Papaleo F. Sannino S, et al. Among authors: manago f. Cereb Cortex. 2015 Sep;25(9):2529-41. doi: 10.1093/cercor/bhu053. Epub 2014 Mar 21. Cereb Cortex. 2015. PMID: 24658585 Free PMC article.
Adolescence is the starting point of sex-dichotomous COMT genetic effects.
Sannino S, Padula MC, Managò F, Schaer M, Schneider M, Armando M, Scariati E, Sloan-Bena F, Mereu M, Pontillo M, Vicari S, Contarini G, Chiabrera C, Pagani M, Gozzi A, Eliez S, Papaleo F. Sannino S, et al. Among authors: manago f. Transl Psychiatry. 2017 May 30;7(5):e1141. doi: 10.1038/tp.2017.109. Transl Psychiatry. 2017. PMID: 28556830 Free PMC article.
Variations in Dysbindin-1 are associated with cognitive response to antipsychotic drug treatment.
Scheggia D, Mastrogiacomo R, Mereu M, Sannino S, Straub RE, Armando M, Managò F, Guadagna S, Piras F, Zhang F, Kleinman JE, Hyde TM, Kaalund SS, Pontillo M, Orso G, Caltagirone C, Borrelli E, De Luca MA, Vicari S, Weinberger DR, Spalletta G, Papaleo F. Scheggia D, et al. Among authors: manago f. Nat Commun. 2018 Jun 11;9(1):2265. doi: 10.1038/s41467-018-04711-w. Nat Commun. 2018. PMID: 29891954 Free PMC article.
The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans.
Leggio GM, Torrisi SA, Mastrogiacomo R, Mauro D, Chisari M, Devroye C, Scheggia D, Nigro M, Geraci F, Pintori N, Giurdanella G, Costa L, Bucolo C, Ferretti V, Sortino MA, Ciranna L, De Luca MA, Mereu M, Managò F, Salomone S, Drago F, Papaleo F. Leggio GM, et al. Among authors: manago f. Mol Psychiatry. 2021 Apr;26(4):1272-1285. doi: 10.1038/s41380-019-0511-4. Epub 2019 Sep 6. Mol Psychiatry. 2021. PMID: 31492942
31 results