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Human gut commensal Alistipes timonensis modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an Il10 -deficient mouse model.
Older EA, Mitchell MK, Campbell A, Lian X, Madden M, Wang Y, van de Wal LE, Zaw T, VanderVeen BN, Tatum R, Murphy EA, Chen YH, Fan D, Ellermann M, Li J. Older EA, et al. Among authors: ellermann m. bioRxiv [Preprint]. 2024 Oct 24:2024.10.23.619966. doi: 10.1101/2024.10.23.619966. bioRxiv. 2024. PMID: 39484420 Free PMC article. Preprint.
Discovery of BAY 2666605, a Molecular Glue for PDE3A and SLFN12.
Lewis TA, Ellermann M, Kopitz C, Lange M, de Waal L, Wu X, Tersteegen A, Denner K, Lienau P, Kaulfuss S, Goldoni S, Meyerson M, Greulich H, Gradl SN. Lewis TA, et al. Among authors: ellermann m. ACS Med Chem Lett. 2024 Sep 10;15(10):1662-1667. doi: 10.1021/acsmedchemlett.4c00336. eCollection 2024 Oct 10. ACS Med Chem Lett. 2024. PMID: 39411532
Biosynthetic Enzyme-guided Disease Correlation Connects Gut Microbial Metabolites Sulfonolipids to Inflammatory Bowel Disease Involving TLR4 Signaling.
Older EA, Zhang J, Ferris ZE, Xue D, Zhong Z, Mitchell MK, Madden M, Wang Y, Chen H, Nagarkatti P, Nagarkatti M, Fan D, Ellermann M, Li YX, Li J. Older EA, et al. Among authors: ellermann m. bioRxiv [Preprint]. 2023 May 2:2023.03.16.533047. doi: 10.1101/2023.03.16.533047. bioRxiv. 2023. Update in: Nat Commun. 2024 Oct 30;15(1):9371. doi: 10.1038/s41467-024-53670-y. PMID: 36993324 Free PMC article. Updated. Preprint.
Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis.
Viladomiu M, Khounlotham M, Dogan B, Lima SF, Elsaadi A, Cardakli E, Castellanos JG, Ng C, Herzog J, Schoenborn AA, Ellermann M, Liu B, Zhang S, Gulati AS, Sartor RB, Simpson KW, Lipkin SM, Longman RS. Viladomiu M, et al. Among authors: ellermann m. Cell Rep. 2022 Nov 15;41(7):111637. doi: 10.1016/j.celrep.2022.111637. Cell Rep. 2022. PMID: 36384110 Free PMC article.
Endocannabinoids Inhibit the Induction of Virulence in Enteric Pathogens.
Ellermann M, Pacheco AR, Jimenez AG, Russell RM, Cuesta S, Kumar A, Zhu W, Vale G, Martin SA, Raj P, McDonald JG, Winter SE, Sperandio V. Ellermann M, et al. Cell. 2020 Oct 29;183(3):650-665.e15. doi: 10.1016/j.cell.2020.09.022. Epub 2020 Oct 7. Cell. 2020. PMID: 33031742 Free PMC article.
38 results